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largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
linear decrease » linear increase (Expand Search)
chain linear » chain linked (Expand Search), chain lower (Expand Search), ha linear (Expand Search)
_ largest » _ large (Expand Search)
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Data Sheet 1_Comparison of carbonic anhydrase-IX-targeted trifunctional radioligands between linear- and branched-chain arrangements.pdf
Published 2025“…The introduction of an albumin binder (ALB) to radioligands can delay their renal clearance, resulting in increased radioactivity delivered to tumors and decreased renal uptake of radioligands. In this study, we designed novel CA-IX-targeted trifunctional radioligands consisting of imidazothiadiazole sulfonamide (IS) as a CA-IX-targeted ligand, DOTA as a chelator with four free carboxylic groups, and lysine-conjugated 4-(p-iodophenyl)butyric acid (Lys-IPBA) as ALB, with IS-[<sup>111</sup>In]In-DOTADG-ALB in a linear-chain arrangement and [<sup>111</sup>In]In-DOTAGA-ALB-IS in a branched-chain arrangement. …”
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Distribution of individual change in trust in science before and after the pandemic (n = 10,000).
Published 2025Subjects: -
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