بدائل البحث:
linear decrease » linear increase (توسيع البحث)
marked decrease » marked increase (توسيع البحث)
chain linear » chain linked (توسيع البحث), chain lower (توسيع البحث), ha linear (توسيع البحث)
linear decrease » linear increase (توسيع البحث)
marked decrease » marked increase (توسيع البحث)
chain linear » chain linked (توسيع البحث), chain lower (توسيع البحث), ha linear (توسيع البحث)
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Data Sheet 1_Comparison of carbonic anhydrase-IX-targeted trifunctional radioligands between linear- and branched-chain arrangements.pdf
منشور في 2025"…The introduction of an albumin binder (ALB) to radioligands can delay their renal clearance, resulting in increased radioactivity delivered to tumors and decreased renal uptake of radioligands. In this study, we designed novel CA-IX-targeted trifunctional radioligands consisting of imidazothiadiazole sulfonamide (IS) as a CA-IX-targeted ligand, DOTA as a chelator with four free carboxylic groups, and lysine-conjugated 4-(p-iodophenyl)butyric acid (Lys-IPBA) as ALB, with IS-[<sup>111</sup>In]In-DOTADG-ALB in a linear-chain arrangement and [<sup>111</sup>In]In-DOTAGA-ALB-IS in a branched-chain arrangement. …"
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ROS, K<sup>+</sup> efflux and cathepsin B are required for NLRP3 activation.
منشور في 2025الموضوعات: -
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Eggs jointly coordinate a caspase-1 and caspase-8 dependent pyroptotic cell death.
منشور في 2025الموضوعات: -
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The loss of NLRP3 and AIM2 results in reduced Th17 and enhanced Th2 cytokine responses.
منشور في 2025الموضوعات: -
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Gsdmd deficiency reduces myeloid cell recruitment to the liver during schistosome infection.
منشور في 2025الموضوعات: -
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