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e decrease » we decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
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marked decrease » marked increase (Expand Search)
e decrease » we decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
hla e » hla a (Expand Search)
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All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex
Published 2024“…In this study, we employed all-atom molecular dynamics simulations to investigate the impact of different membrane compositions on the conformational dynamics of the NKG2A/CD94/HLA-E immune receptor complex, a key negative regulator of natural killer cell cytotoxic activity. …”
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Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 5_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 7_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 4_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 8_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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