Search alternatives:
marked decrease » marked increase (Expand Search)
ca decrease » a decrease (Expand Search), la decreased (Expand Search), pa decreased (Expand Search)
via ca » via cu (Expand Search), via ct (Expand Search), via casp (Expand Search)
marked decrease » marked increase (Expand Search)
ca decrease » a decrease (Expand Search), la decreased (Expand Search), pa decreased (Expand Search)
via ca » via cu (Expand Search), via ct (Expand Search), via casp (Expand Search)
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Data Sheet 1_Long-term gabapentin treatment impairs cognitive function in aged mice via tau hyperphosphorylation.docx
Published 2025“…In the hippocampus of GBP-treated mice, increased levels of p-tau (S416) and p-tau (S262) were observed, together with increased CaMKIIα and decreased Sirt1 expression. AAV-mediated Sirt1 overexpression in the hippocampus or systemic administration of the Sirt1 activator resveratrol prevented cognitive impairment and tau hyperphosphorylation via enhancing Sirt1 activity in GBP-treated mice.…”
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Hydrogen inhibits fibroblast differentiation into myofibroblasts via TGF-β1/Smad2/3 pathway.
Published 2025Subjects: -
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Hydrogen ameliorates AngII-induced electrical remodeling of HL-1 cells via NOX4/ROS/NLRP3 pathway.
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Proposed mechanism of action of ibuprofen (IBU) on hypoxic cancer cells.
Published 2025“…<p>IBU impairs the STAT3 pathway and downregulates HIF-1α protein leading to impaired HIF-1 binding on the <i>CA9</i> promoter. The disruption of CA IX transcription results in a decreased level of CA IX on cancer cell membrane. …”
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Mechanism of H<sub>2</sub> inhibition on AngII-mediated AF and atrial fibrosis.
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Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…Synaptic mitochondria appear to rely mainly on mCa<sup>2+</sup> efflux via mNCE, while non-synaptic mitochondria rely mainly on P<sub>i</sub>-dependent mCa<sup>2+</sup> sequestration. …”