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e decrease » we decrease (Expand Search), _ decrease (Expand Search), a decrease (Expand Search)
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All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex
Published 2024“…In this study, we employed all-atom molecular dynamics simulations to investigate the impact of different membrane compositions on the conformational dynamics of the NKG2A/CD94/HLA-E immune receptor complex, a key negative regulator of natural killer cell cytotoxic activity. …”
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Data Sheet 1_Use of HLA desensitization in the management of renal transplant recipients in Europe.pdf
Published 2025“…The results indicate high variation in what physicians consider to be the threshold mean fluorescence intensity (MFI) level for significant anti-HLA antibodies and the need for desensitization. …”
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Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 5_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Data Sheet 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 7_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 4_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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Image 8_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg
Published 2025“…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27<sup>pos</sup>), AS+AAU (HLA-B27<sup>pos</sup>), AAU (HLA-B27<sup>pos</sup>), HCs (HLA-B27<sup>pos</sup>), and HCs (HLA-B27<sup>neg</sup>); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …”
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