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marked decrease » marked increase (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search), fold increases (Expand Search)
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Truncated and Disubstituted (P4K and L7R) Oncocin Peptides Target the Ribosome with Improved Antibacterial Activity
Published 2025“…A cell-based plasmid expression system was deployed in Escherichia coli (E. coli) to gain direct knowledge of structure–activity relationships with truncated and/or disubstituted (P4K and L7R) oncocin variants. We identified a shortened oncocin sequence that maintained antibiotic activity and favorable cationic amino acid substitutions that led to a 2-fold decrease in the minimum inhibitory concentration (MIC) compared to the parent 19mer oncocin sequence. …”
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Heatmap comparison of the highest fractional inhibitory concentration index (FICI) values and fold change (FC) reductions in colistin MIC across all tested bacterial strains.
Published 2025“…<p>(A) depicts strain-specific synergy between FTIs and colistin, with lonafarnib and tipifarnib exhibiting the strongest effects against gram-negative bacteria such as <i><i>E. cloacae</i></i> and <i><i>K. pneumoniae</i></i>. (B) highlights fold changes in colistin MIC, showcasing substantial reductions, including a 32-fold decrease in <i><i>B. subtilis</i></i> (with lonafarnib) and <i><i>E. cloacae</i></i> (with both lonafarnib and tipifarnib). …”
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Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments
Published 2025“…Incorporation of poly(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m<sup>3</sup>) with almost similar tensile strength. …”
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Upcycling of Postconsumer Recyclate Polypropylene into Low Warping and High Toughness 3D Printable Filaments
Published 2025“…Incorporation of poly(butylene adipate-<i>co</i>-terephthalate) (PBAT) along with maleic anhydride grafted polypropylene (MAPP) in specific proportions led to a significant enhancement in mechanical properties, miscibility, crystallization behavior, and 3D printability. rPP/PBAT blends with 20 wt % PBAT and 10 wt % MAPP exhibited a 62-fold enhancement in elongation at break over rPP (from 1.88 to 118.29%) and a 72-fold increase in toughness (from 2 to 143.60 kJ/m<sup>3</sup>) with almost similar tensile strength. …”