Tetrandrine decreases Mtb antigen presentation. حسب Elham Karamooz (2584474)

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex حسب Martin Ljubič (15680161)

"…In this study, we employed all-atom molecular dynamics simulations to investigate the impact of different membrane compositions on the conformational dynamics of the NKG2A/CD94/HLA-E immune receptor complex, a key negative regulator of natural killer cell cytotoxic activity. …"

Data Sheet 1_Use of HLA desensitization in the management of renal transplant recipients in Europe.pdf حسب Lionel P. E. Rostaing (22138330)

"…As the degree of sensitization increases, the likelihood of finding a compatible organ decreases. Desensitization is the process of reducing recipient anti-HLA antibodies to acceptable levels to allow transplantation. …"

Data Sheet 1_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf حسب Marc-Antoine Béland (20294229)

"…Introduction<p>De novo donor-specific HLA antibody (dnDSA) are associated with poor outcomes. …"

Data Sheet 2_HLA class, calcineurin inhibitor levels, and the risk of graft failure in kidney recipients with de novo donor-specific antibodies.pdf حسب Marc-Antoine Béland (20294229)

"…Introduction<p>De novo donor-specific HLA antibody (dnDSA) are associated with poor outcomes. …"

ZIKV infection enriches the HLA Class I pathway in brain tumour cells. حسب Matt Sherwood (22530221)

"…Normalised enrichment score (NES) denotes the degree to which the enrichment increased (+) or decreased (-). GSEA analysis significance is defined by p ≤ 0.05 and FDR ≤ 0.25. …"

Data Sheet 1_Case Report: HLA-DRB1 04:01 found in a child with adenovirus type 2 -linked hepatitis.pdf حسب Yoshiki Katsumi (11586237)

"…Adeno-associated virus type 2 (AAV2) was identified as a cause, with most affected children having the HLA-DRB1 04:01 genotype. In this study, we hypothesized that HLA-DRB1 04:01 in the host may also be a potential predisposing factor of acute hepatitis caused by other viruses. …"

Data Sheet 2_Case Report: HLA-DRB1 04:01 found in a child with adenovirus type 2 -linked hepatitis.pdf حسب Yoshiki Katsumi (11586237)

"…Adeno-associated virus type 2 (AAV2) was identified as a cause, with most affected children having the HLA-DRB1 04:01 genotype. In this study, we hypothesized that HLA-DRB1 04:01 in the host may also be a potential predisposing factor of acute hepatitis caused by other viruses. …"

Image 6_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 9_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Data Sheet 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.docx حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 5_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Data Sheet 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Data Sheet 3_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.xlsx حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 7_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 1_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 2_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 4_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"

Image 8_Divergent B-cell and cytotoxic TNK cell activation signatures in HLA-B27-associated ankylosing spondylitis and acute anterior uveitis.jpeg حسب Eisa Mahyari (9681962)

"…Using cellular indexing of transcriptomes and epitopes (CITE-Seq) in a well-characterized cohort of 25 subjects—including AS (HLA-B27^pos), AS+AAU (HLA-B27^pos), AAU (HLA-B27^pos), HCs (HLA-B27^pos), and HCs (HLA-B27^neg); N = 5/group—we identified transcriptomic differences at the single-cell level, along with differentially expressed cell surface markers. …"