Showing 1 - 20 results of 79 for search '(( ct ((largest decrease) OR (marked decrease)) ) OR ( car ((sites decrease) OR (we decrease)) ))', query time: 0.52s Refine Results
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    Data Sheet 1_Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells.docx by Aida López Ruiz (21611177)

    Published 2025
    “…To address this need, in this work, we utilized a bioinspired, scalable, tunable platform to direct T-cell activation and decrease exhaustion during CAR T production.…”
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    Image 1_Emapalumab for severe cytokine release syndrome in solid tumor CAR-T: a case report.tif by Tyler Ruemmele (20972594)

    Published 2025
    “…Here we report a patient who received an investigational CAR-T product for metastatic castration-resistant prostate cancer who developed multi-drug refractory, life-threatening CRS, which was successfully treated with the interferon (IFN)-γ antagonist emapalumab. …”
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    Table 2_Hyper-fractionated radiotherapy as a bridging strategy to enhance CAR-T efficacy by regulating T-cell co-stimulatory molecules in relapsed/refractory diffuse large B-cell l... by Jing Ruan (5117951)

    Published 2024
    “…After T-cell collection, the patients underwent hyper-fractionated radiotherapy at lesion sites with 1.5 Gy twice daily for 10 days before CAR-T cell infusion. …”
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    Table 1_Hyper-fractionated radiotherapy as a bridging strategy to enhance CAR-T efficacy by regulating T-cell co-stimulatory molecules in relapsed/refractory diffuse large B-cell l... by Jing Ruan (5117951)

    Published 2024
    “…After T-cell collection, the patients underwent hyper-fractionated radiotherapy at lesion sites with 1.5 Gy twice daily for 10 days before CAR-T cell infusion. …”
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    Table 3_Hyper-fractionated radiotherapy as a bridging strategy to enhance CAR-T efficacy by regulating T-cell co-stimulatory molecules in relapsed/refractory diffuse large B-cell l... by Jing Ruan (5117951)

    Published 2024
    “…After T-cell collection, the patients underwent hyper-fractionated radiotherapy at lesion sites with 1.5 Gy twice daily for 10 days before CAR-T cell infusion. …”
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    Presentation 1_HNF4α contributes to hepatic CAR dysfunction in polymicrobial sepsis.pptx by Céline Van Dender (22080545)

    Published 2025
    “…Additionally, we show that CAR DNA binding is impaired, and we propose that HNF4α may regulate chromatin accessibility of CAR binding sites in sepsis. …”
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    Data Sheet 1_GSTP1 improves CAR-T cell proliferation and cytotoxicity to combat lymphoma.zip by Guangsong Xu (22315933)

    Published 2025
    “…Based on these findings, we engineered GSTP1 CAR-T cells, which exhibited improved functionality. …”
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    Development of production methodologies for scFv-Fc conjugated critical reagents to support CAR-T clinical programs by Ellen O’Connor (3597413)

    Published 2025
    “…</p> <p>We highlight our approach in developing process conditions for CAR-T supporting conjugated critical reagents, where recombinant CAR scFv-hFc is the surrogate drug material to be conjugated. …”
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    Data Sheet 1_Effect of music therapy on children with autism spectrum disorders in the Chinese population: a systematic review and meta-analysis.docx by Yajing Yang (2105431)

    Published 2025
    “…The results showed that MT significantly decreased the total ATEC (autism treatment evaluation checklist) score (SMD = -2.52, 95% CI: -3.69 ~ -1.35, P < 0.001), ABC (autism behavior checklist) (SMD = -1.07, 95% CI: -1.52 ~ -0.61, P < 0.001), and CARS (childhood autism rating scale) score (SMD = -1.50, 95% CI: -2.26 ~ -0.74, P < 0.001). …”
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    Data Sheet 1_Empagliflozin’s cardioenergetic protective effects through PPARα pathway modulation in heart failure.pdf by Hua Wei (60877)

    Published 2025
    “…Post-treatment, MRGlu and glucose uptake decreased markedly in the empagliflozin (EMPG) group, while no significant changes were observed in the fenofibrate (FF) group. …”
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    Table_1_FMT intervention decreases urine 5-HIAA levels: a randomized double-blind controlled study.DOCX by Lihong Wang (14991)

    Published 2024
    “…The average GSRS scores decreased from 30.17 (before) to 19 (after; p < 0.0001), CARS scores decreased from 36.22 to 33.33 (p < 0.0001), SRS scores decreased from 151.17 to 137.5 (p = 0.0002), and the ABC scores decreased 76.39 to 53.17 (p < 0.0001) in the FMT group. …”
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    DataSheet1_A novel strategy of co-expressing CXCR5 and IL-7 enhances CAR-T cell effectiveness in osteosarcoma.docx by Xinhui Hui (4889578)

    Published 2024
    “…On the other hand, IL-7 improves the survival and persistence of T cells inside a solid tumor milieu.</p>Methods<p>We constructed a novel NKG2D-based CAR (C5/IL7-CAR) that co-expressed CXCR5 and IL-7. …”
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    DataSheet1_Prognostic significance of fludeoxyglucose positron emission tomography delta radiomics following bridging therapy in patients with large B-cell lymphoma undergoing CAR... by Colton Ladbury (19768281)

    Published 2024
    “…</p>Materials/methods<p>We retrospectively reviewed patients with LBCL treated with bRT followed by CAR T-cell therapy. …”
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