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largest decrease » largest decreases (Expand Search), larger decrease (Expand Search)
marked decrease » marked increase (Expand Search)
dcas also » can also (Expand Search)
largest decrease » largest decreases (Expand Search), larger decrease (Expand Search)
marked decrease » marked increase (Expand Search)
dcas also » can also (Expand Search)
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Urine dicarboxylic acids change in pre-symptomatic Alzheimer’s disease and reflect loss of energy capacity and hippocampal volume
Published 2020“…Moreover, mean C4-C5 DCAs were lower and mean C7-C9 were higher in urine from CH individuals with abnormal compared to normal CSF amyloid and Tau levels; i.e., the apparent urine changes in AD also appeared to be present in CH individuals that have CSF risk factors of early AD pathology. …”
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GFP to BFP repair assay to detect DNA damage induced by dCas9-KR.
Published 2020“…For comparison, nuclease proficient Cas9 plus gRNA were also used. <b>(E)</b> dCas9-KR activation in Olaparib treated cells did not increase NHEJ (GFP<sup>–</sup>) rates, and therefore NHEJ is relatively unaffected or occurring at levels that are too low to be detected by this assay. …”
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