Search alternatives:
largest decrease » larger decrease (Expand Search)
marked decrease » marked increase (Expand Search)
reader decrease » greater decrease (Expand Search), teer decrease (Expand Search), greatest decrease (Expand Search)
largest decrease » larger decrease (Expand Search)
marked decrease » marked increase (Expand Search)
reader decrease » greater decrease (Expand Search), teer decrease (Expand Search), greatest decrease (Expand Search)
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The m6A reader YTHDF2 protects vascular smooth muscle cells against the osteogenic differentiation through targeting Runx2
Published 2025“…The M6A-modified mRNA degradation process is mediated by the reader YTHDF2 in an m6A-dependent manner. …”
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A lysine-restricted diet ameliorates obesity via enrichment of Parabacteroides goldsteinii and 1,4-methylimidazoleacetic acid
Published 2025“…Metabolomics revealed that P. goldsteinii increases 1,4-methylimidazoleacetic acid (MIAA), a metabolite linked to decreased body weight in animal models. Mechanistically, we show that MIAA inhibits the expression of the demethylase FTO, leading to increased m6A modifications on Slc2a4 mRNA via the reader protein YTHDC1. …”
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Data Sheet 1_Landscape analysis of m6A modification regulators reveals LRPPRC as a key modulator in tubule cells for DKD: a multi-omics study.docx
Published 2025“…GSVA showed that the two types of m6a regulation, namely m6a-readers and m6a-writers, were generally suppressed in DKD patients. …”
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Data Sheet 1_Empagliflozin’s cardioenergetic protective effects through PPARα pathway modulation in heart failure.pdf
Published 2025“…Post-treatment, MRGlu and glucose uptake decreased markedly in the empagliflozin (EMPG) group, while no significant changes were observed in the fenofibrate (FF) group. …”
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(A-H). Case 1: primary subcutaneous facial alveolar echinococcosis.
Published 2025“…<p><b>(A)</b> Left frontal swelling at diagnosis. <b>(B)</b> Marked regression of the lesion after 6 months of albendazole therapy. …”
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Image 1_MLL4 regulates postnatal palate growth and midpalatal suture development.tif
Published 2025“…Immunofluorescence staining for osteochondral differentiation markers demonstrated a marked decrease in the chondrogenic marker COL2A1, while the expression of the osteogenic marker RUNX2 remained unchanged, in the Mll4-cKO midpalatal suture. …”
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Data Sheet 1_MLL4 regulates postnatal palate growth and midpalatal suture development.csv
Published 2025“…Immunofluorescence staining for osteochondral differentiation markers demonstrated a marked decrease in the chondrogenic marker COL2A1, while the expression of the osteogenic marker RUNX2 remained unchanged, in the Mll4-cKO midpalatal suture. …”
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Table 1_Coptis japonica Makino ethanol extracts attenuates cancer cachexia induced muscle and fat wasting through inhibition of the STAT3 signaling pathway.docx
Published 2025“…Our results demonstrated that CJME significantly decreased the mRNA and protein levels of muscle-specific E3 ubiquitin ligases Atrogin-1 and MuRF1 in myotubes exposed to CT26 CM. …”