(A) Immobility time, (B) Frozen events for forced swim test. by Hammad Ismail (4227988)

(A) Serotonin and (B) Dopamine levels in brain tissues. by Hammad Ismail (4227988)

(A) Time spent in light compartment, (B) Number of transitions between compartments, (C) Number of head pokes to light compartment for light-dark compartment test. by Hammad Ismail (4227988)

(A) Mobility rate, (B) Explored areas, (5C) Immobility time, (D) Frozen events for hole board test. by Hammad Ismail (4227988)

(A) Duration of contacts, (B) Distance covered, (C) Number of interacting contacts, (D) Number of frozen events for social interaction test. by Hammad Ismail (4227988)

(A) Number of crossings, (B) Number of rearings, (C) Latency time for novel object, (D) Familiar object exploration time, (E) Novel object exploration time for novel object recogni... by Hammad Ismail (4227988)

(A) Time taken to reach platform in hidden trail, (B) Time taken to reach platform in visible trail, (C) Latency time to reach platform zone and (D) Time spent in platform zone in... by Hammad Ismail (4227988)

(A) Time spent in closed arm, (B) Time spent in open arm, (C) Number of entries in closed arm, (D) Number of entries in open arm, and (E) Latency time to enter open arm for elevate... by Hammad Ismail (4227988)

Vps34 orchestrates Treg function in vivo. by Erienne G. Norton (9612079)

Targeting of Vps34 reduces B16F10 tumor growth and working model for Vps34-dependent regulation of eTreg transitional heterogeneity and maintenance. by Erienne G. Norton (9612079)

Loss of Vps34 reduces Treg suppressive function and is associated with the development of type-I-dominant inflammatory disease. by Erienne G. Norton (9612079)

Vps34 supports Treg maintenance in lymphoid and non-lymphoid tissues. by Erienne G. Norton (9612079)

Atg14 does not contribute to terminal eTreg generation during perinatal life. by Erienne G. Norton (9612079)

Chromatin accessibility analysis of perinatal Vps34-deficient Tregs. by Erienne G. Norton (9612079)

“…(<b>C</b>) GSEA enrichment plot showing decreased Hallmark TNFα signaling via NFκB signature in Vps34-deficient versus control terminal eTregs from single-cell transcriptome profiling (as described in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3003074#pbio.3003074.g003" target="_blank">Fig 3</a>). …”

Atg14 plays a cell-intrinsic role in orchestrating eTreg survival but not terminal differentiation. by Erienne G. Norton (9612079)

Vps34 orchestrates transcriptional and epigenetic remodeling events corresponding to terminal eTreg differentiation during perinatal life. by Erienne G. Norton (9612079)

“…Top transcription factors with predicted decreased activity are labeled, including AP-1-related transcription factors. …”

Analysis of Tregs from perinatal mice and mixed BM chimeras for transitional and terminal eTreg states. by Erienne G. Norton (9612079)

Uvrag in Tregs is dispensable for establishment of immune tolerance and eTreg accumulation. by Erienne G. Norton (9612079)

Targeting of Vps34 or Atg14, but not Uvrag, in Tregs reduces tumor growth in mouse models. by Erienne G. Norton (9612079)

Atg14 deficiency in Tregs induces a type-I-dominant lymphoproliferative disease and cell-intrinsic reductions in eTregs. by Erienne G. Norton (9612079)