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661
Kit-mediated autophagy suppression driven by a viral oncoprotein emerges as a crucial survival mechanism in Merkel cell carcinoma
Published 2025“…</p> <p><b>Abbreviation</b>: 3-MA, 3-methyladenine; AL, autolysosome; AP, autophagosome; Baf-A1, bafilomycin A<sub>1</sub>; BARA, β-α repeated autophagy specific domain; BH3, BCL2 homology 3 domain; CCD, coiled-coil domain; CHX, cycloheximide; Co-IP, co-immunoprecipitation; CQ, chloroquine; CTR, control; DAPI, 4′,6-diamidino-2-phenylindole; EBSS, Earle’s balanced salt solution; ECD, evolutionarily conserved domain; EEE, three-tyrosine phosphomimetic mutations Y229E Y233E Y352E; ER, endoplasmic reticulum; FFF, three-tyrosine non-phosphomimetic mutations; FFPE, formalin-fixed paraffin-embedded; FL, full-length; GIST, gastrointestinal stromal tumor; IB, immunoblotting; IHC, immunohistochemistry; KIT-HEK293, KIT stably expressing HEK293 cells; KRT20/CK20, keratin 20; LT, large T-antigen; LT339, MCPyV truncated LT antigen; LTco, codon-optimized MCPyV LT antigen; MCC, Merkel cell carcinoma; MCPyV<sup>−</sup>, MCPyV-negative; MCPyV, Merkel cell polyomavirus; MCPyV<sup>+</sup>, MCPyV-positive; PARP1, poly(ADP-ribose) polymerase 1; PCI, pan-caspase inhibitor; PI, propidium iodide; PtdIns3K, class III phosphatidylinositol 3-kinase; PtdIns3P, phosphatidylinositol-3-phosphate; RB1, RB transcriptional corepressor 1; RTKs, receptor tyrosine kinases; KITLG/SCF, KIT ligand; sT, small T-antigen; sTco, codon-optimized MCPyV sT antigen; T-B, Tat-BECN1; T-S, Tat-scrambled; TEM, transmission electron microscopy.…”
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662
Evaluation results.
Published 2024“…<div><p>Spectral Photon Counting Computed Tomography (SPCCT), a ground-breaking development in CT technology, has immense potential to address the persistent problem of metal artefacts in CT images. …”
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663
Dataset with steel insert.
Published 2024“…<div><p>Spectral Photon Counting Computed Tomography (SPCCT), a ground-breaking development in CT technology, has immense potential to address the persistent problem of metal artefacts in CT images. …”
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664
Reference dataset.
Published 2024“…<div><p>Spectral Photon Counting Computed Tomography (SPCCT), a ground-breaking development in CT technology, has immense potential to address the persistent problem of metal artefacts in CT images. …”
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665
Dataset with aluminium insert.
Published 2024“…<div><p>Spectral Photon Counting Computed Tomography (SPCCT), a ground-breaking development in CT technology, has immense potential to address the persistent problem of metal artefacts in CT images. …”
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666
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668
Continuous Viscoelasticity Measurement of Cell Spheroids via Microfluidic Electrical Aspiration
Published 2024Subjects: -
669
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670
Primers used for RT-PCR.
Published 2025“…</p><p>Results</p><p>BLM caused a large decrease in body weight in mice. However, the intraperitoneal injection of SS-31 slowed down the body weight loss in the mice. …”
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671
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672
Data Sheet 1_Increased risk of deep vein thrombosis, pulmonary embolism, and all-cause mortality in chronic venous disorder: a large-scale retrospective cohort study.docx
Published 2025“…Comparing CVD patients with interventions to those without, the risk of DVT (0.9, 0.8–0.9), PE (0.6, 0.5–0.6) and all-cause mortality (0.5, 0.5–0.5) decreased. Conversely, the risk of SVT increased (1.8, 1.6–2.0).…”
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673
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Supplementary Material for: Allopurinol Use is Associated With Decreased Incidence of Hepatic Decompensation and Overall Mortality Among Individuals With Cirrhosis: a Propensity-ma...
Published 2025“…This study aims to evaluate the association of allopurinol use with the incidence of hepatic decompensation and overall mortality in patients with cirrhosis in a large, propensity-matched cohort. Methods: A retrospective cohort study of adults with cirrhosis was conducted using the national TriNetX database, with 1:1 propensity score matching. …”
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675
Data Sheet 1_Cytotoxic CD4+ T-follicular cells may mediate killing against lymphoma cells.pdf
Published 2025“…In contrast, DLBCL exhibited a decrease in T<sub>FH</sub> and T<sub>FR</sub> cell numbers, while concurrently demonstrating heightened frequencies of GZMK<sup>+</sup>TIA-1<sup>+</sup> and especially GZMB<sup>+</sup>TIA-1<sup>+</sup> T<sub>F</sub><sub>K</sub> cells within the T<sub>FH</sub> population. …”
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676
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680
Variables of trees located at coordinates .
Published 2025“…Some rare species may persist through rapid evolution to tolerate or escape new threats, but representing the underlying ecological and evolutionary processes at the appropriate scale is analytically and computationally challenging. <i>Tillandsia utriculata</i> has been classified as endangered in Florida where its population has decreased significantly due to predation by the invasive Mexican weevil <i>Metamasius callizona</i>. …”