Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…<p>(A) Gene Set Enrichment Analysis (GSEA) was conducted to identify the major enriched pathways of differentially expressed genes following PARP9 downregulation. …”

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

“…<i>P</i> < 0.05, |log₂ fc| > log₂ (1.5)] modulated ones are indicated with name. Niraparib decreases CYP51A1 (lanosterol 14α-demethylase) enzyme levels (Supplementary Fig. …”

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…</p><p></p> <p>MTX has a negative effect on ovarian follicle reserve in rats</p> <p>Curcumin, with its antioxidant activity, prevents MTX-induced follicle loss through the p53 and PARP-1 mediated pathway.…”

Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells. by Yating Li (1819822)

“…<p>(A) The correlation between PARP9 and SOX6 was validated using an online database. …”

Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer by Li-Li Long (14963775)

“…<p>LKB1 deficiency impairs IFNγ pathway by hindering STAT1 phosphorylation. (a) Western blotting for detection of LKB1 and pAMPK expression in K and KL lung tumors. …”

Decreased hypotaurine levels within cells lacking the ADO gene in U251 cells. by Hong Tian (169626)

The linearly decreasing convergence factor a. by Junhao Wei (6816803)

Table 1_Effect of decreased suspended sediment content on chlorophyll-a in Dongting Lake, China.docx by Le Zhang (88249)

“…The reduction in SSC may influence chlorophyll-a (Chl-a) concentrations in water, thereby further affecting the aquatic ecological environment. …”

Naringenin decreases mitochondrial function. by Lauren A. Eanes (20995499)

Predicting pattern diversity decreases as a function of and . by Selim Haj Ali (21222613)

“…(b) and (d): Average proportion of cases predicted as pattern diversity decreases for and , respectively for and .</p>…”

BrdU incorporation is elevated in clrn1-/- zebrafish at 4 mpf and decreases with age. by Hannah J. T. Nonarath (20861735)

“…<p>Anti-BrdU (green) staining in paraffin sections from (a,a’) 4 mpf, (b,b’) 8 mpf, (c,c’) 12 mpf, and (d,d’) 20 mpf in wild-type and <i>clrn1</i>^<i>-/-</i> zebrafish retinas. …”

Naringenin decreases total cell viability. by Lauren A. Eanes (20995499)

CaMKKβ is involved in ST2-104-regulated decrease in autophagy. by Yingshi Ji (9013004)