Search alternatives:
values decrease » values increased (Expand Search), largest decrease (Expand Search)
parp decrease » pa decreased (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
ct values » _ values (Expand Search), i values (Expand Search)
values decrease » values increased (Expand Search), largest decrease (Expand Search)
parp decrease » pa decreased (Expand Search), step decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
ct values » _ values (Expand Search), i values (Expand Search)
-
1
Inotodiol decreases clone formation in HCC cells.
Published 2025“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”
-
2
-
3
-
4
-
5
PARP9 knockdown promotes apoptosis and DNA damage.
Published 2024“…<p>(A) Gene Set Enrichment Analysis (GSEA) was conducted to identify the major enriched pathways of differentially expressed genes following PARP9 downregulation. …”
-
6
-
7
Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf
Published 2025“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”
-
8
-
9
Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx
Published 2025“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”
-
10
Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf
Published 2025“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”
-
11
Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation
Published 2025“…<i>P</i> < 0.05, |log<sub>2</sub> fc| > log<sub>2</sub> (1.5)] modulated ones are indicated with name. Niraparib decreases CYP51A1 (lanosterol 14α-demethylase) enzyme levels (Supplementary Fig. …”
-
12
-
13
Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53
Published 2024“…</p><p></p> <p>MTX has a negative effect on ovarian follicle reserve in rats</p> <p>Curcumin, with its antioxidant activity, prevents MTX-induced follicle loss through the p53 and PARP-1 mediated pathway.…”
-
14
Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells.
Published 2024“…<p>(A) The correlation between PARP9 and SOX6 was validated using an online database. …”
-
15
-
16
-
17
CT Values of reference materials.
Published 2025“…The research results show that coal core in the region where minerals exist has a higher density, while the density of the coal matrix is smaller. …”
-
18
Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer
Published 2025“…<p>LKB1 deficiency impairs IFNγ pathway by hindering STAT1 phosphorylation. (a) Western blotting for detection of LKB1 and pAMPK expression in K and KL lung tumors. …”
-
19
Image 7_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif
Published 2025“…Diagnosing malignant small lung nodules (≤3cm) in CT scans remains a challenge in clinical practice.…”
-
20
Image 6_Exploration of the diagnostic and prognostic roles of decreased autoantibodies in lung cancer.tif
Published 2025“…Diagnosing malignant small lung nodules (≤3cm) in CT scans remains a challenge in clinical practice.…”