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    Stability of the Arginine–Ornithine–Citrulline Cycle Maintained by Tumor–Stroma Interactions in Cell Coculture Hydrogel Microspheres by Hongren Yao (8857088)

    Published 2023
    “…In addition, an interesting phenomenon was discovered; in the absence of fibroblasts, the metabolism of the tumor cell culture alone leads to arginine depletion and citrulline accumulation, whereas a coculture can maintain the arginine–ornithine–citrulline cycle to reach equilibrium after 72 h, and the balance increases the stress resistance of tumor cells. …”