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441
Table_1_Platycodin D and voluntary running synergistically ameliorate memory deficits in 5 × FAD mice via mediating neuromodulation and neuroinflammation.DOCX
Published 2024“…In addition, the PD and voluntary running combination reduced Aβ build-up, decreased hyperactivation of microglia and astrocytes in the hippocampus and perirhinal cortex, promoted the polarization of inflammatory M1 microglia and reactive astrocytes toward beneficial phenotypes, and lowered systemic circulating pro-inflammatory cytokines while increasing anti-inflammatory cytokines in 5 × FAD mice. …”
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442
Change in semantic entropy over time by number of rounds of Council deliberation needed for consensus.
Published 2025“…Semantic entropy trajectories reveal distinct deliberation patterns: fast-converging questions (2-3 rounds, steep slopes ≤ -0.25) versus slow-converging questions (5 + rounds, gradual slopes ≤ -0.05). Incorrect consensus outcomes show more erratic entropy patterns compared to smooth, predictable decreases in correct consensus cases. …”
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443
Table 1_Moso bamboo invasion alters soil microbial nutrient limitation by modifying plant diversity and soil nutrient cycling in subtropical forest.docx
Published 2025“…These microbial nutrient limitation changes correspond with reduced tree litter and increased shrub/herb presence. …”
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444
Data Sheet 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…<p>Sarcopenia is a chronic, progressive disease characterized by the gradual loss of skeletal muscle strength and mass. …”
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445
Supplementary file 1_Regulation of SLC7A11 by LncRNA GPRC5D-AS1 mediates ferroptosis in skeletal muscle: Mechanistic exploration of sarcopenia.pdf
Published 2025“…<p>Sarcopenia is a chronic, progressive disease characterized by the gradual loss of skeletal muscle strength and mass. …”
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446
Table 4_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…It also decreased the mRNA expression of Pik3cg, Akt1, Pdk1 and Nfκb1.…”
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447
Table 2_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.docx
Published 2025“…It also decreased the mRNA expression of Pik3cg, Akt1, Pdk1 and Nfκb1.…”
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448
Table 1_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…It also decreased the mRNA expression of Pik3cg, Akt1, Pdk1 and Nfκb1.…”
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449
Table 3_The ultrafine powder of atractylodis macrocephalae rhizoma improves immune function in naturally aging rats by regulating the PI3K/Akt/NF-κB signaling pathway.xlsx
Published 2025“…It also decreased the mRNA expression of Pik3cg, Akt1, Pdk1 and Nfκb1.…”
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450
Table 2_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…These findings suggest a gradual improvement in the underlying condition. The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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451
Table 4_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…These findings suggest a gradual improvement in the underlying condition. The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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452
Supplementary file 1_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…These findings suggest a gradual improvement in the underlying condition. The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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453
Table 1_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…These findings suggest a gradual improvement in the underlying condition. The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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454
Table 3_Meta-analysis of the efficacy of rituximab in the management of cryoglobulinemic vasculitis.docx
Published 2025“…These findings suggest a gradual improvement in the underlying condition. The levels of IgM were significantly reduced following treatment (MD = −0.48, 95%CI: −0.65, −0.31), both at 6-month (MD = −1.05, 95%CI: −1.57, −0.52) and 12-month (MD = −0.59, 95%CI:−0.80, −0.38) follow-ups. …”
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455
Data Sheet 1_Prolonged heat stress in Brassica napus during flowering negatively impacts yield and alters glucosinolate and sugars metabolism.docx
Published 2025“…Results showed that heat stress reduced yield and altered oil composition. Heat stress also increased the content of carbohydrate (glucose, fructose, and sucrose) and aliphatic glucosinolates (gluconapin and progoitrin) in the leaves but decreased the content of the indolic glucosinolate (glucobrassicin). …”
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456
Data Sheet 1_Higher estimated dietary intake of live microbes is associated with lower mortality in US adults.docx
Published 2025“…In the RCS analysis, the relationship between TDIIM and all-cause mortality exhibited a non-linear pattern with a gradual decline followed by a plateau at higher intakes, while a linear decreasing trend was observed with CVD mortality. …”
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457
Supplementary file 1_Bibliometrics-guided cyberpharmacology and transcriptomics for multidimensional analysis of the antihepatic fibrosis mechanism of kaempferol.docx
Published 2025“…Introduction<p>Hepatic Fibrosis (HF), a pathological remodeling process triggered by persistent liver damage, is marked by the excessive buildup of extracellular matrix (ECM), leading to a gradual deterioration of liver function and an increased likelihood of advancing to cirrhosis and liver failure.…”
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458
Image 1_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…Since, non-synaptic mitochondria displayed a significantly reduced ss[Ca<sup>2+</sup>]<sub>e</sub>, this suggested a larger mCa<sup>2+</sup> buffering capacity to maintain [Ca<sup>2+</sup>]<sub>m</sub> with increasing mCa<sup>2+</sup> loads. …”
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459
Image 2_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…Since, non-synaptic mitochondria displayed a significantly reduced ss[Ca<sup>2+</sup>]<sub>e</sub>, this suggested a larger mCa<sup>2+</sup> buffering capacity to maintain [Ca<sup>2+</sup>]<sub>m</sub> with increasing mCa<sup>2+</sup> loads. …”
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460
Image 3_Differential Ca2+ handling by isolated synaptic and non-synaptic mitochondria: roles of Ca2+ buffering and efflux.tif
Published 2025“…Since, non-synaptic mitochondria displayed a significantly reduced ss[Ca<sup>2+</sup>]<sub>e</sub>, this suggested a larger mCa<sup>2+</sup> buffering capacity to maintain [Ca<sup>2+</sup>]<sub>m</sub> with increasing mCa<sup>2+</sup> loads. …”