بدائل البحث:
degrader therapeutics » derived therapeutics (توسيع البحث), dental therapeutics (توسيع البحث)
decrease therapeutic » increased therapeutic (توسيع البحث), great therapeutic (توسيع البحث), directed therapeutic (توسيع البحث)
heat resistance » host resistance (توسيع البحث), plant resistance (توسيع البحث), high resistance (توسيع البحث)
decrease heat » release heat (توسيع البحث)
degrader therapeutics » derived therapeutics (توسيع البحث), dental therapeutics (توسيع البحث)
decrease therapeutic » increased therapeutic (توسيع البحث), great therapeutic (توسيع البحث), directed therapeutic (توسيع البحث)
heat resistance » host resistance (توسيع البحث), plant resistance (توسيع البحث), high resistance (توسيع البحث)
decrease heat » release heat (توسيع البحث)
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Table_1_Sublethal heat treatment enhances lactic acid uptake in macrophages via MCT1, leading to reduced paraspeckle formation and a subsequent decrease in macrophage pyroptosis.xl...
منشور في 2024"…Additionally, PKM2 was identified as a key molecule in this context, with decreased levels after sublethal heat treatment in the presence of lactic acid.…"
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DataSheet1_Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood.PDF
منشور في 2024"…</p>Conclusion<p>Our data provided two therapeutical options capable of preventing the impact of an early drug initiation during adolescence by decreasing voluntary ethanol consumption in adult rats</p>…"
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Hepatosomatic index % (a); Spleen somatic index % (b) in tilapia in different experimental groups.
منشور في 2023الموضوعات: -
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Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations
منشور في 2024"…More importantly, the degradation-based therapeutic modality can overcome on-target mutation resistance to tyrosine kinase inhibitors by efficient degradation of the mutated kinase to achieve greater potency than inhibition.…"
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Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy
منشور في 2024"…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
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Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy
منشور في 2024"…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
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136
Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy
منشور في 2024"…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
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Table_1_Physiological and Transcriptome Analysis of Exogenous L-Arginine in the Alleviation of High-Temperature Stress in Gracilariopsis lemaneiformis.XLSX
منشور في 2021"…These results may help in understanding the role of Arg in G. lemaneiformis resistance to HT and provide a practical viewpoint for obtaining heat-tolerant G. lemaneiformis to further promote the development of the cultivated seaweed industry in the future.…"
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Data_Sheet_1_Physiological and Transcriptome Analysis of Exogenous L-Arginine in the Alleviation of High-Temperature Stress in Gracilariopsis lemaneiformis.docx
منشور في 2021"…These results may help in understanding the role of Arg in G. lemaneiformis resistance to HT and provide a practical viewpoint for obtaining heat-tolerant G. lemaneiformis to further promote the development of the cultivated seaweed industry in the future.…"
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Table_1_The CaChiVI2 Gene of Capsicum annuum L. Confers Resistance Against Heat Stress and Infection of Phytophthora capsici.DOCX
منشور في 2020"…Here, for the first time it was discovered that CaChiVI2 (Capana08g001237) gene of pepper (Capsicum annuum L.) had a role in resistance to heat stress and physiological processes. …"