يعرض 121 - 140 نتائج من 1,674 نتيجة بحث عن '(( decrease heat resistance ) OR ( ((decrease therapeutic) OR (degrader therapeutics)) options ))', وقت الاستعلام: 0.59s تنقيح النتائج
  1. 121

    Table_1_Sublethal heat treatment enhances lactic acid uptake in macrophages via MCT1, leading to reduced paraspeckle formation and a subsequent decrease in macrophage pyroptosis.xl... حسب Zhuoyang Fan (491761)

    منشور في 2024
    "…Additionally, PKM2 was identified as a key molecule in this context, with decreased levels after sublethal heat treatment in the presence of lactic acid.…"
  2. 122

    DataSheet1_Cannabidiol or ketamine for preventing the impact of adolescent early drug initiation on voluntary ethanol consumption in adulthood.PDF حسب Carles Colom-Rocha (19487494)

    منشور في 2024
    "…</p>Conclusion<p>Our data provided two therapeutical options capable of preventing the impact of an early drug initiation during adolescence by decreasing voluntary ethanol consumption in adult rats</p>…"
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    S1 Data - حسب Sinthia Kabir Mumu (17705902)

    منشور في 2023
    الموضوعات:
  8. 128

    S2 Data - حسب Sinthia Kabir Mumu (17705902)

    منشور في 2023
    الموضوعات:
  9. 129
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    Fig 4 - حسب Sinthia Kabir Mumu (17705902)

    منشور في 2023
    الموضوعات:
  12. 132

    Discovery of Oral Degraders of the ROS1 Fusion Protein with Potent Activity against Secondary Resistance Mutations حسب Xianyou Peng (2130313)

    منشور في 2024
    "…More importantly, the degradation-based therapeutic modality can overcome on-target mutation resistance to tyrosine kinase inhibitors by efficient degradation of the mutated kinase to achieve greater potency than inhibition.…"
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    Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy حسب Lu Huang (211625)

    منشور في 2024
    "…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
  15. 135

    Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy حسب Lu Huang (211625)

    منشور في 2024
    "…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
  16. 136

    Development of Oral, Potent, and Selective CK1α Degraders for AML Therapy حسب Lu Huang (211625)

    منشور في 2024
    "…These findings indicate that phenotypic drug discovery campaigns, in combination with chemically distinct CRBN ligand libraries, can accelerate the development of therapeutically relevant MGDs. Furthermore, the development of dCK1α-1 and dCK1α-2 provides new therapeutic options for cancers with functional p53 signaling and offers valuable chemical tools for future investigations into the role of CK1α.…"
  17. 137

    Table_1_Physiological and Transcriptome Analysis of Exogenous L-Arginine in the Alleviation of High-Temperature Stress in Gracilariopsis lemaneiformis.XLSX حسب Jun Zhang (48506)

    منشور في 2021
    "…These results may help in understanding the role of Arg in G. lemaneiformis resistance to HT and provide a practical viewpoint for obtaining heat-tolerant G. lemaneiformis to further promote the development of the cultivated seaweed industry in the future.…"
  18. 138

    Data_Sheet_1_Physiological and Transcriptome Analysis of Exogenous L-Arginine in the Alleviation of High-Temperature Stress in Gracilariopsis lemaneiformis.docx حسب Jun Zhang (48506)

    منشور في 2021
    "…These results may help in understanding the role of Arg in G. lemaneiformis resistance to HT and provide a practical viewpoint for obtaining heat-tolerant G. lemaneiformis to further promote the development of the cultivated seaweed industry in the future.…"
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    Table_1_The CaChiVI2 Gene of Capsicum annuum L. Confers Resistance Against Heat Stress and Infection of Phytophthora capsici.DOCX حسب Muhammad Ali (266260)

    منشور في 2020
    "…Here, for the first time it was discovered that CaChiVI2 (Capana08g001237) gene of pepper (Capsicum annuum L.) had a role in resistance to heat stress and physiological processes. …"