Showing 101 - 120 results of 7,831 for search '(( decrease heat resistance ) OR ( ((decrease therapy) OR (increased therapy)) resistance ))*', query time: 0.47s Refine Results
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    DataSheet_1_Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.pdf by Meike Kaehler (4561306)

    Published 2023
    “…</p>Results<p>In this model, acquired sequence variants in NRAS, KRAS, PTPN11, and PDGFRB were identified in TKI resistance. The well-known pathogenic NRAS p.(Gln61Lys) variant provided a strong benefit for CML cells under TKI exposure visible by increased cell number (6.2-fold, p < 0.001) and decreased apoptosis (-25%, p < 0.001), proving the functionality of our approach. …”
  11. 111

    DataSheet_1_PARP Inhibition Activates STAT3 in Both Tumor and Immune Cells Underlying Therapy Resistance and Immunosuppression In Ovarian Cancer.pdf by Antons Martincuks (11800829)

    Published 2021
    “…Finally, we demonstrate that the acquisition of PARPi resistance in ovarian cancer cells was accompanied by increased STAT3 activity. …”
  12. 112

    DataSheet_1_PARP Inhibition Activates STAT3 in Both Tumor and Immune Cells Underlying Therapy Resistance and Immunosuppression In Ovarian Cancer.pdf by Antons Martincuks (11800829)

    Published 2021
    “…Finally, we demonstrate that the acquisition of PARPi resistance in ovarian cancer cells was accompanied by increased STAT3 activity. …”
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