Interleukin 6 is increased in preclinical HNSCC models of acquired cetuximab resistance, but is not required for maintenance of resistance by Rachel A. O’Keefe (8269389)

“…We found that IL-6 secretion was increased in PE/CA-PJ49 cells that had acquired resistance to cetuximab compared to the parental cells from which they were derived. …”

Percentages of concentration changes in TNF-α, IL-6, and IFN-γ in co-culture of hypoxic and normoxic PANC-1 cells with CD8+ T-cells. by Eiman Abdo (20642254)

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Relative expression levels in TNF-α, IL-6, and p53 in co-culture and CM treatment of hypoxic and normoxic PANC-1 cells with CD8+ T-cells. by Eiman Abdo (20642254)

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Percentages (%) of concentration changes in TNF-α, IL-6, and IFN-γ released by PANC-1 cells under hypoxic and normoxic conditions cultured with CD8+ T-cells CM. by Eiman Abdo (20642254)

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Heat map showing the correlations between different parameters with the respective correlation coefficient (r) values. by Rege Anna Márton (18536676)

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Cell line models of acquired cetuximab resistance exhibit increased IL-6 secretion. by Rachel A. O’Keefe (8269389)

IL-21R blockade increases resistance to <i>L</i>. <i>sigmodontis</i>. by Johanna A. Knipper (8103317)

Supplementary Table 1 from Targeting ULK1 Decreases IFNγ-Mediated Resistance to Immune Checkpoint Inhibitors by Sarah E. Fenton (15062814)

Effect of CD8+ T-cells coculture and CM on hypoxic and normoxic PANC-1 cells. by Eiman Abdo (20642254)

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CFSE staining of CD8+ T-cells for proliferation assessment. by Eiman Abdo (20642254)

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CD8+ T-cells percentage in PBMCs and purity after isolation and activation. by Eiman Abdo (20642254)

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Assessment of CD8+ T-cells viability after activation and culturing in HCM vs. NCM for 72 hours by staining with 7-AAD. by Eiman Abdo (20642254)

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Percentages (%) of concentration changes of cytokines for CD8+ T-cells after cultured in HCM or NCM of PANC-1 cells. by Eiman Abdo (20642254)

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SRC-3 treatment decreased tumor growth in a Jeko-1 ibrutinib resistant mouse model. by Imani Bijou (18275174)

Related Article from Myeloid Suppressors Decrease Melanoma Survival by Abating Tumor-Fighting T Cells by Rolf Kiessling (149724)

Figure 5 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)

“…<b>H,</b> The cells were loaded with the lysosomal fluorescent probes LysoPrime Green (the pH-resistant probe) and pHLys Red (the pH-sensitive probe; Dojindo Laboratories) and treated with increasing concentrations of NH₄Cl in the imaging medium or bafilomycin A as a control. …”

Diet-induced obesity increases the concentration of <i>L</i>. <i>major</i> specific immunoglobulins in C57BL/6 serum. by Vinicius Dantas Martins (8282220)

Figure 6 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)

Figure 2 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)

Figure 3 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin by Joanna Domagala (21643925)