Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

Heat transfer measurements of Polyalpha-Olefin- boron nitride nanofluids for thermal management and lubrication applications by Ahmad K. Sleiti (14778229)

“…Two competing phenomena affect the heat transfer performance: the increase/decrease in resistance to thermal diffusion sublayer when thermal conductivity increases and viscosity decreases, respectively. …”

Microbial Dysbiosis Tunes the Immune Response Towards Allergic Disease Outcomes by Tracy Augustine (14149932)

“…<p>The hygiene hypothesis has been popularized as an explanation for the rapid increase in allergic disease observed over the past 50 years. …”

Editorial: Dynamic Biomarkers of Response to Anti-Immune Checkpoint Inhibitors in Cancer by Said Dermime (79420)

“…One promising emerging approach is to focus on dynamic biomarkers, which would allow, when tested in the patient early after exposition to the therapeutic agents, to identify those patients presenting an immune response failure. …”

Thermally Conductive Polyethylene/Expanded Graphite Composites as Heat Transfer Surface: Mechanical, Thermo-Physical and Surface Behavior by Patrik Sobolčiak (4401364)

“…<p dir="ltr">Composites of high-density polyethylene (HDPE) and expanded graphite (EG) are prepared for heat exchangers in multi-effect distillation (MED) desalination. …”

Targeting arginine auxotrophy in pancreatic cancer cells using human recombinant arginase I-induced arginine deprivation. (c2017) by Khalil, Nathalie

“…Therefore, there’s a need for more effective and selective therapeutic approaches for targeting PC. In this study, we examined the mechanisms of arginine auxotrophy in PC cell lines. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Hence, HuArgI (Co)-PEG5000 is an efficient and selective therapeutic method for targeting GBM.…”
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Metformin Induces Different Responses in Clear Cell Renal Cell Carcinoma Caki Cell Lines by Mazhar Pasha (11197767)

“…Our study unveils the therapeutic potential of metformin to inhibit the progression of ccRCC in vitro. …”

Unleashing the immune response to NY-ESO-1 cancer testis antigen as a potential target for cancer immunotherapy by Afsheen Raza (492657)

“…We propose that combination therapy to increase the efficacy of NY-ESO-1 specific immunotherapeutic interventions should be explored to unleash the immune response against NY-ESO-1 expressing tumors.…”

Targeting of lactate dehydrogenase C dysregulates the cell cycle and sensitizes breast cancer cells to DNA damage response targeted therapy by Adviti Naik (673163)

“…LDHC‐silenced cells demonstrated aberrant cell cycle progression with differential expression of cell cycle checkpoint and DNA damage response regulators. In addition, LDHC silencing‐induced microtubule destabilization, culminating in increased mitotic catastrophe and reduced long‐term survival. …”

MicroRNA-24-3p Targets Notch and Other Vascular Morphogens to Regulate Post-ischemic Microvascular Responses in Limb Muscles by Micol Marchetti (18623410)

“…Exposure to hypoxia increased miR-24-3p in ECs but not in pericytes. Transfection with a miR-24-3p precursor (pre-miR-24-3p) increased miR-24-3p expression in ECs, reducing the cell survival, proliferation, and angiogenic capacity. …”

Sesamum indicum (sesame) enhances NK anti-cancer activity, modulates Th1/Th2 balance, and suppresses macrophage inflammatory response by Majdalawieh, Amin

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Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy by Khoury, Reine

“…The results reveal the potential therapeutic benefits of plasma factors released in response to exercise in an autophagy dependent manner.…”
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Graphite and metal nitrate-infused HDPE composites for enhanced thermal performance in energy-efficient building envelopes by Mohammad Amir Khan (23770803)

“…These results point to a scalable approach for developing lightweight corrosion resistant thermal management composites that can be used in the design of energy efficient wall panels and heat-dissipative building materials.…”

Ultrasound Triggered Release of Estrone- Targeted Liposomes by Kawak, Pierre

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DNAJB3/HSP-40 cochaperone improves insulin signaling and enhances glucose uptake in vitro through JNK repression by Mohamed Abu-Farha (25322)

“…<p dir="ltr">Heat shock response (HSR) is an essential host-defense mechanism that is dysregulated in obesity-induced insulin resistance and type 2 diabetes (T2D). …”

Circulating exosomal immuno-oncological checkpoints and cytokines are potential biomarkers to monitor tumor response to anti-PD-1/PD-L1 therapy in non-small cell lung cancer patien... by Shayista Akbar (14442117)

“…Identification of biomarkers associated with responses are mandated in order to increase the efficacy of such therapy. …”

Adipocyte Enhancer-Binding Protein 1 (AEBP1) (a Novel Macrophage Proinflammatory Mediator) Overexpression Promotes and Ablation Attenuates Atherosclerosis in ApoE⁻′⁻ and LDLR⁻′⁻ Mi... by Bogachev, Oleg

“…Atherogenesis is a long-term process that involves inflammatory response coupled with metabolic dysfunction. Foam cell formation and macrophage inflammatory response are two key events in atherogenesis. …”
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Isolation and study of Lipase activity of an olive oil degrading Thermoactionomyces SP. (c2002) by Al Khudary, Rami

“…This lipolytic enzyme showed resistance to boiling and to a wide range of metallic 10ns and inhibitors. …”
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Characterization of Dse1 a candida albicans cells wall protein. (c2009) by Daher, Jalil Y.

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