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Elucidating the Probiotic Potential of <i>Lactobacillus</i> and <i>Bifidobacterium</i> Species in Modulating Glucose Metabolism and Inflammation in Gestational Diabetes Mellitus: A...
Published 2025“…The evidence indicates the potential of <i>Lactobacillus</i>- and <i>Bifidobacterium</i>-based probiotic interventions to beneficially influence glucose metabolism, inflammatory response, and gut microbial balance in GDM. Heterogeneity in probiotic formulations across studies, probiotic doses, and regional differences in diet and lifestyle underscore the need for more targeted and standardized research to fully understand the therapeutic potential of probiotics in GDM.…”
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62
Extramedullary haematopoiesis in patients with transfusion dependent β-thalassaemia (TDT): a systematic review
Published 2022“…However, there are increasingly reported cases of EMH in BTM. The incidence of EMH in BTM is thought to be <1%. …”
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63
Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
Published 2024“…These findings underscore the roles of miR-222-5p and miR-21-3p as potential regulators of FliC-induced inflammation and provide insight into the molecular mechanisms underlying C. difficile-associated inflammatory responses. Future studies could explore their therapeutic potential in mitigating intestinal inflammation in vivo in mouse model of C. difficile infections.…”
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64
Immunomodulatory effects of tumor Lactate Dehydrogenase C (LDHC) in breast cancer
Published 2025“…</p><h3>Conclusions</h3><p dir="ltr">Our findings suggest that targeting LDHC could enhance anti-tumor immune responses by modulating cytokine and chemokine secretion in addition to impairing immune checkpoint signaling. …”
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65
The Kinetics of Calcein Release from Mixed Targeted Liposomes Using Ultrasound
Published 2022“…Site-specific delivery of chemotherapeutics using actively targeted-stimuli-responsive liposomes is a promising approach to enhance the therapeutic efficiency of anti-cancer drugs while reducing the associated undesirable side effects. …”
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66
Role of cytokines and platelet-activating factor in inflammatory bowel disease
Published 1996“…Cytokines are peptides that regulate and coordinate inflammatory and immunologic responses. Increased production of cytokines has been reported during Crohn's disease and ulcerative colitis and is correlated with disease activity. …”
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Noncoding RNAs in Nonalcoholic Fatty Liver Disease: Potential Diagnosis and Prognosis Biomarkers
Published 2020“…<p>Nonalcoholic fatty liver disease (NAFLD) is currently the most common chronic liver disease worldwide in part due to the concomitant obesity pandemic and insulin resistance (IR). It is increasingly becoming evident that NAFLD is a disease affecting numerous extrahepatic vital organs and regulatory pathways. …”
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68
Synergistic Effects of Nanomedicine Targeting TNFR2 and DNA Demethylation Inhibitor—An Opportunity for Cancer Treatment
Published 2019“…From an epigenetic perspective, previous studies indicate that DNA demethylation might be responsible for high expressions of TNFR2 in cancer models. …”
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69
Microbial and operational factors affecting energy recovery potential for anaerobic membrane bioreactors treating different wastewater types
Published 2022“…It was found that for such high-strength wastewaters, energy expenditure for substrate heating or electrical demand is negligible in comparison to the potential variability in methane production rates achievable.…”
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70
Arsenic: A double-edged sword
Published 2014“…Research shows that As<sub>2</sub>O<sub>3</sub><sub> </sub>increases intracellular calcium ion concentration irreversibly. …”
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71
Profiling the autoantibody repertoire reveals autoantibodies associated with mild cognitive impairment and dementia
Published 2023“…And 20 proteins had significantly altered autoantibody responses in MCI compared to cognitively normal individuals. …”
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72
Cancer cell plasticity: from cellular, molecular, and genetic mechanisms to tumor heterogeneity and drug resistance
Published 2024“…This diversity, known as cancer cell plasticity, confers cancer cells the ability to change in response to their environment, leading to increased tumor diversity and drug resistance. …”
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73
Evaluation of the durability and shielding properties of high-strength concrete incorporating locally available materials and carbon additives
Published 2026“…Furthermore, conductive concrete exhibits enhanced electrical properties, enabling its use in specialized applications such as heating, electromagnetic shielding, and antistatic systems. …”
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74
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
Published 2021“…A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. …”
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75
Metal-based nanoparticles: Promising tools for the management of cardiovascular diseases
Published 2021“…A search for more effective treatments of CVD is increasingly needed. Major advances in nanotechnology opened new avenues in CVD therapeutics. …”
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76
SIRT1 promotes lipid metabolism and mitochondrial biogenesis in adipocytes and coordinates adipogenesis by targeting key enzymatic pathways
Published 2021“…Supplementing preadipocytes with the NAD+ booster nicotinamide mononucleotide (NMN) during differentiation increased expression levels of leptin, SIRT1, and PGC-1α and its transcriptional targets, and reduced levels of pro-fibrotic collagens (Col6A1 and Col6A3) in a SIRT1-dependent manner. …”