Search alternatives:
degrader therapeutics » derived therapeutics (Expand Search), dental therapeutics (Expand Search)
decrease therapeutic » increased therapeutic (Expand Search), great therapeutic (Expand Search), directed therapeutic (Expand Search)
host resistance » plant resistance (Expand Search)
decrease host » decreases short (Expand Search)
degrader therapeutics » derived therapeutics (Expand Search), dental therapeutics (Expand Search)
decrease therapeutic » increased therapeutic (Expand Search), great therapeutic (Expand Search), directed therapeutic (Expand Search)
host resistance » plant resistance (Expand Search)
decrease host » decreases short (Expand Search)
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DataSheet1_Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination.pdf
Published 2022“…Functional characterization revealed that givinostat effect was related to autophagic pathway inhibition, unveiling new theories concerning degradation pathways of misfolded SG proteins. Beyond the identification of a new therapeutic option for LGMD R3 patients, our results shed light on the potential repurposing of givinostat for the treatment of other genetic diseases sharing similar protein degradation defects such as LGMD R5 and cystic fibrosis.…”
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DataSheet2_Dual Blockade of Misfolded Alpha-Sarcoglycan Degradation by Bortezomib and Givinostat Combination.pdf
Published 2022“…Functional characterization revealed that givinostat effect was related to autophagic pathway inhibition, unveiling new theories concerning degradation pathways of misfolded SG proteins. Beyond the identification of a new therapeutic option for LGMD R3 patients, our results shed light on the potential repurposing of givinostat for the treatment of other genetic diseases sharing similar protein degradation defects such as LGMD R5 and cystic fibrosis.…”
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Food supplementation affects gut microbiota and immunological resistance to parasites in a wild bird species
Published 2019“…Furthermore, supplemental feeding could induce resistance to detrimental parasites (e.g. invasive parasites) in hosts when management of the parasite is not immediately possible. …”
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CDK4/6 inhibition presents as a therapeutic option for pediatric and adult germ cell tumors and induces cell cycle arrest and apoptosis via canonical and non-canonical mechanisms
Published 2020“…</p><p><b>Conclusion:</b> Our study highlights PaRi as therapeutic options for cisplatin-resistant and -sensitive pediatric and adult GCTs. …”
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Data_Sheet_2_The Effect of Host Immunity on Predicting the Mortality of Carbapenem-Resistant Organism Infection.docx
Published 2020“…<p>Carbapenem-resistant organisms (CROs) are associated with considerable mortality clinically. …”
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Data_Sheet_1_The Effect of Host Immunity on Predicting the Mortality of Carbapenem-Resistant Organism Infection.PDF
Published 2020“…<p>Carbapenem-resistant organisms (CROs) are associated with considerable mortality clinically. …”
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Parasite invasion and acute virulence were reduced in the Δ<i>crt</i> parasites.
Published 2019Subjects: -
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