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increased tumor » increased number (Expand Search), increased time (Expand Search)
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increased tumor » increased number (Expand Search), increased time (Expand Search)
i resistance » _ resistance (Expand Search), high resistance (Expand Search), acid resistance (Expand Search)
decrease i » decrease _ (Expand Search), decreases _ (Expand Search), decreased _ (Expand Search)
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Figure 5 from Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
Published 2025“…<b>G,</b> The level of perforin detected in NK cells incubated with NH<sub>4</sub>Cl and other lysosomotropic agents [chloroquine (CQ), concanamycin (CMA), and monensin] for 4 hours determined by intracellular staining using antibodies detecting total perforin (B-D48 clone) and lysosomal perforin (δG9 clone; <i>n</i> = 2). <b>H,</b> The cells were loaded with the lysosomal fluorescent probes LysoPrime Green (the pH-resistant probe) and pHLys Red (the pH-sensitive probe; Dojindo Laboratories) and treated with increasing concentrations of NH<sub>4</sub>Cl in the imaging medium or bafilomycin A as a control. …”
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DataSheet_1_Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors.zip
Published 2022“…<p>Response to immunotherapy across multiple cancer types is approximately 25%, with some tumor types showing increased response rates compared to others (i.e. response rates in melanoma and non-small cell lung cancer (NSCLC) are typically 30-60%). …”
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DataSheet_2_Increased tumor glycolysis is associated with decreased immune infiltration across human solid tumors.zip
Published 2022“…<p>Response to immunotherapy across multiple cancer types is approximately 25%, with some tumor types showing increased response rates compared to others (i.e. response rates in melanoma and non-small cell lung cancer (NSCLC) are typically 30-60%). …”
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Inotodiol decreases clone formation in HCC cells.
Published 2025“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”
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