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Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes
Published 2023“…<p dir="ltr">Several pathways and/or genes have been shown to be dysregulated in obesity-induced insulin resistance (IR) and type 2 diabetes (T2D). We previously showed, for the first time, impaired expression of DNAJB3 mRNA and protein in subjects with obesity, which was concomitant with increased metabolic stress. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Glioblastoma multiforme (GBM) is a highly aggressive glioma arising in the central nervous system accounting for more than 70% of all brain tumors. Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. …”
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masterThesis -
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A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries
Published 2024“…</p><h3>Conclusion</h3><p dir="ltr">Generalized morphea with concomitant EF indicates some degree of therapeutic resistance and poor prognosis with a low quality of life. …”