A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate by Geethakumari, Anupriya M

“…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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Risk Factors for Post-Cesarean, Surgical Site Infections in a Multi-Ethnic Population of Qatar by Sufia Athar (14777830)

“…<h3>Background</h3><p dir="ltr">The surgical site infection (SSI) rate after Cesarean delivery (CD) is considered one of the key performance indicators, not only for developing and under-developed countries but also for developed nations. …”

Regional variations in incidence of surgical site infection and associated risk factors in women undergoing cesarean section: A systematic review and Meta-Analysis by Nazmul, Islam

“…BackgroundSurgical site infections (SSIs) are the most common postoperative complications after cesarean section (CS), with increased mortality, prolonged hospital stays, and increased healthcare costs. …”
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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…</p><h3>Conclusion</h3><p dir="ltr">Hypoglycemia potentiated both plasma sNRP1 level elevation and its ligands VEGF and SEMA3A, likely through an ADAM9-mediated mechanism that was not associated with RAS overactivity or ACEi therapy; however, whether this is protective or promotes increased risk for SARS-CoV-2 infection in T2D is unclear.…”

HbA1c over 8.5% is not predictive of increased infection rate following penile prosthesis implant surgery in diabetic patients with erectile dysfunction by Raidh Talib (14779198)

“…<p dir="ltr">Diabetes mellitus is associated with increased risk of erectile dysfunction. Penile prosthesis implantation is an efficient therapeutic option for erectile dysfunction, but not without risk, as infection remains a prominent concern. …”

Increased leptin expression in mice with bacterial peritonitis is partially regulated by tumor necrosis factor alpha by Abdalla, Eddie

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Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin–angiotensin-aldosterone system (RAAS) dysregulation by Robin Augustine (3976964)

Topical Vancomycin for Prevention of Surgical Site Infection after Craniotomy: Meta-analysis and Systematic Literature Review by Ahmed Saleh (3150639)

“…<h3>Objective</h3><p dir="ltr">There is no consensus among neurosurgeons regarding whether the application of topical vancomycin after performing craniotomy has a role in reduction of the risk of surgical site infection and consequently reduction of treatment costs. …”

The emergence of new SARS-CoV-2 variant (Omicron) and increasing calls for COVID-19 vaccine boosters-The debate continues by Naushad Ahmad Khan (6406973)

“…The emergence of these VOCs (Alpha, Beta, Gamma, and Delta) variants was responsible for new waves of infections across the entire world [3]. The Delta variant was reported to have increased transmissibility, higher viral load [4] and high rates of reinfection [5]. …”

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…Significantly lower NP test scores was observed in HIC than those of HUC. HIC showed decreased FA and increased MD in multiple brain sites as compared to both CHNM and HUC. …”
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Age–sex differences in the global burden of lower respiratory infections and risk factors, 1990–2019: results from the Global Burden of Disease Study 2019 by Hmwe Hmwe Kyu (8674014)

“…<h3>Background</h3><p dir="ltr">The global burden of lower respiratory infections (LRIs) and corresponding risk factors in children older than 5 years and adults has not been studied as comprehensively as it has been in children younger than 5 years. …”

Molecular pattern of acquiring upper respiratory infection by Mohamed A. Hendaus (9401919)

“…Among the key factors influencing the seasonality of these infections, variations in temperature and absolute humidity are critical elements driving the increase in respiratory virus infections, particularly during the winter months. …”

New epidemiology of Staphylococcus aureus infections in the Middle East by Tokajian, S.

“…Staphylococcus aureus is a bacterial pathogen that is distributed worldwide and represents an increasing problem, both in hospitals and in the community. …”
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The effects of needleless connectors on catheter-related bloodstream infections by Btaiche, Imad F.

“…Negative and positive displacement mechanical valves have been associated with increased rates of catheter-related bloodstream infections as compared with split septum connectors. …”
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Relationship Between Hyperglycemia and Infection in Critically Ill Patients by Btaiche, Imad F.

“…Uncontrolled hyperglycemia may be associated with complications such as fluid and electrolyte disturbances and increased infection risk. Studies have demonstrated impairment of host defenses, including decreased polymorphonuclear leukocyte mobilization, chemotaxis, and phagocytic activity related to hyperglycemia. …”
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Genome-Based Characterization of Bacterial Pathogens Causing Bloodstream Infection by Boujanian, Carni

“…Bloodstream infections (BSIs) caused by multi-drug resistant (MDR) bacterial pathogens are considered among the risk factors that pose a severe threat to public health, leading to increased morbidity and mortality. …”
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A 75-year-old female with hemoptysis and recurrent respiratory infections by Diab, Khalil

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Adherence to international guidelines for the treatment of uncomplicated urinary tract infections in Lebanon by Kabbara, Wissam K.

“…Conclusions. In an era of increasing bacterial resistance, interventions that improve physicians’ prescribing practices for uncomplicated urinary tract infections are needed.…”
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Microbiome profiling of rotavirus infected children suffering from acute gastroenteritis by Muhammad U. Sohail (9522515)

“…</p> <h2>Results</h2> <p>The data demonstrated a significant increase in microbiome diversity denoted by higher relative abundances of phylum Proteobacteria (p = 0.031), Fusobacteria (p = 0.044) and genus Streptococcus (p ≤ 0.001) in the infected group relative to the control. …”

Strategies to manage hepatitis C virus infection disease burden – volume 3 by Mokhbat, J. E.

“…The hepatitis C virus (HCV) epidemic was forecasted through 2030 for 15 countries in Europe, the Middle East and Asia, and the relative impact of two scenarios was considered: [1] increased treatment efficacy while holding the annual number of treated patients constant and [2] increased treatment efficacy and an increased annual number of treated patients. …”
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