Comparative analysis of human and mouse ovaries across age, DOI: 10.1126/science.adx0659, Seurat Object of subsetted C57BL/6 Mouse Oocytes from this study (GSE290742) merged with t... by Diana Laird (22671017)

“…<p dir="ltr">The mouse is a tractable model for human ovarian biology, however its utility is limited by incomplete understanding of how transcription and signaling differ interspecifically and with age. …”

Table 1_Integrated multi-omics analysis reveals the mechanisms of naringin in ameliorating high-fat diet-induced metabolic dysfunction-associated steatotic liver disease.doc by Wenping Sun (1465360)

“…However, its underlying mechanisms remain largely elusive.</p>Methods<p>In this study, we investigated the efficacy and underlying mechanisms of Nar in a mouse model of high-fat diet (HFD)-induced MASLD using integrated analyses of network pharmacology, molecular docking, hepatic lipidomics, and gut microbiota.…”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Image 2_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 6_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 4_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 5_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 3_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Image 1_Low-frequency electroacupuncture attenuates methamphetamine-induced depressive-like behaviors and cognitive impairment via modulating neuroinflammation.tif by Jingyi Zhang (741111)

“…Electroacupuncture (EA) has shown promise in treating mental disorders linked to CNS damage, yet the effects of EA on METH-induced depressive-like behaviors and cognitive impairment and it’s underlying therapeutic mechanisms remain largely unclear.</p>Methods<p>In this study, a mouse model of METH-induced neuropsychiatric dysfunction was established by administering high-dose METH under elevated ambient temperature. …”

Data Sheet 1_Trifolin inhibits the calcium-driven contraction pathway in vascular smooth muscle.pdf by Renfeng Li (126284)

“…<p>Trifolin, a bioactive component of the Qingda granule, has demonstrated significant antihypertensive potential; however, its precise mechanisms of action remain largely unknown. …”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Deficiency of the UBE2C/F264 Axis Underlies Intrinsic Radioresistance in Cervical Carcinoma by Maowei Ni (15397932)

“…Intrinsic radiotherapy resistance remains a persistent challenge to the treatment of cervical cancer (CC), as the underlying mechanisms remain largely elusive. …”

Data Sheet 1_Distinct Arnica montana L. extracts modulate human T cell activation in different ways via differential inhibition of NFκB and NFAT pathways.zip by Karina M. Berschneider (14001561)

“…<p>Arnica montana L. (Arnica) has a long history of use in treating inflammation and soft tissue injury, yet its immunomodulatory mechanisms remain largely unexplored. …”

Image 1_Analgesic effect of Dahuang Fuzi Decoction in neuropathic pain through inhibiting TNF-α and PI3K-AKT signaling.jpeg by Jinglian Qu (10044263)

“…A chronic sciatic nerve compression injury (CCI) rat mode was used to assess the analgesic efficacy of DF for NeP. …”

Tropical fishes can benefit more from novel than familiar species interactions at their cold-range edges by Angus Mitchell (8391018)

“…Whether such novel species interactions facilitate or inhibit range extensions remains largely unknown.</p><p dir="ltr">2. We evaluated how range-extending tropical and co-shoaling temperate fishes modify their behaviours (aggression, foraging, and anti-predator) along a 2,000-km latitudinal gradient encapsulating tropical, subtropical and temperate reefs in a global ocean warming hotspot.…”

Data Sheet 1_Itaconate and obesity-related hormones promote tumor progression – new insights on metabolic dysfunction in early-onset colon cancer.docx by Katharina M. Scheurlen (21507602)

“…Introduction<p>Obesity is a strong risk factor for early-onset colon cancer (EOCC) and is associated with chronic inflammation largely mediated by macrophages. …”

DataSheet1_Anaerobic membrane bioreactor (AnMBR) with external ultrafiltration membrane for the treatment of sugar beet vinasse.PDF by Beatriz Egerland Bueno (20143764)

“…Due to complete sludge retention, AnMBRs achieve high COD removal efficiencies, yielding a suspended solids-free and largely disinfected effluent. …”

Supplementary file 1_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma... by Huijie Lai (22696685)

“…Ethnopharmacological relevance<p>Shaoyao Gancao Decoction (SGD) is a renowned traditional Chinese medicinal formulation widely utilized in Asia. …”

Supplementary file 2_Shaoyao gancao decoction induces autophagy by modulating miR-21 and inhibiting the AKT/mTOR signaling pathway in adenomyosis-derived ectopic endometrial stroma... by Huijie Lai (22696685)

“…Ethnopharmacological relevance<p>Shaoyao Gancao Decoction (SGD) is a renowned traditional Chinese medicinal formulation widely utilized in Asia. …”

Data_Sheet_1_Banxia-Yiyiren alleviates insomnia and anxiety by regulating the gut microbiota and metabolites of PCPA-induced insomnia model rats.zip by Liang Wang (23021)

“…Objective<p>This study aims to clearly define the effects of Banxia-Yiyiren on the gut microbiota and its metabolites in a para-chlorophenylalanine-induced insomnia model and the possible underlying mechanisms involved.…”