Image1_Lipid profiling of RON and DEK-dependent signaling in breast cancer guides discovery of gene networks predictive of poor outcomes.tif by Sara Vicente-Muñoz (13730629)

“…Lipid-related genes were then queried to define a signature that predicts poor outcomes for patients with breast cancer patients. …”

Ultimate Lateral resistance of Tetrapod Pile Foundation in Rate-dependent and Strain-softening Clay by Zi-hao Zhao (21085578)

“…The results show that the ultimate lateral resistance gradually decreases with <b>a reduction in</b> strain-dependent parameters. …”

Table 1_Drug tapering in animal research: current practices and challenges.docx by Yatong Zhang (10114667)

“…</p>Conclusion<p>The methods of drug tapering in animal studies are influenced by multiple factors, including disease characteristics, treatment duration, animal tolerance, and specific goals. There remains a need for further refinement in tapering schedules, methods, and milestones, and the establishment of relevant evaluation metrics to better define tapering timing.…”

Metabolome at time-points during and after pregnancy in NW and OB women. by Ulrika Andersson-Hall (8965229)

“…<p>The first two components in a PCA showing 362 measured NW and OB samples, after removal of one outlier, using 25 metabolite NMR concentration measurements. …”

Assessing sleep homeostasis in real-world data. by Balaji Goparaju (22379158)

“…Example of repeated sleep restriction protocol (SR), with decreased sleep opportunity. C. Schematic of real-world sleep data, aligned to the start of each night for visual convenience, to visualize the approach to computing the baseline (median; dotted line) and defining short night (S) threshold (gray dotted line), and the next night (N) analyzed for homeostatic response. …”

Image 1_Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease.tif by Aaron D. Thome (12907298)

“…After stratification by Hoehn & Yahr (H&Y) stage, inflammatory transcripts IL-6, IL-1β, ARG1, CD163, and CCR2 were upregulated in PD monocytes and increased with disease burden. Furthermore, PPARGC1A (PGC-1α), GPX4, NFE2L2 (NRF2), and SIRT3 decreased with increasing disease burden, while only SIRT1 expression increased, reflecting oxidative stress and mitochondrial dysregulation. …”

Table 1_Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease.xlsx by Aaron D. Thome (12907298)

“…After stratification by Hoehn & Yahr (H&Y) stage, inflammatory transcripts IL-6, IL-1β, ARG1, CD163, and CCR2 were upregulated in PD monocytes and increased with disease burden. Furthermore, PPARGC1A (PGC-1α), GPX4, NFE2L2 (NRF2), and SIRT3 decreased with increasing disease burden, while only SIRT1 expression increased, reflecting oxidative stress and mitochondrial dysregulation. …”

Image 2_Peripheral monocyte transcriptional signatures of inflammation and oxidative stress in Parkinson’s disease.tif by Aaron D. Thome (12907298)

“…After stratification by Hoehn & Yahr (H&Y) stage, inflammatory transcripts IL-6, IL-1β, ARG1, CD163, and CCR2 were upregulated in PD monocytes and increased with disease burden. Furthermore, PPARGC1A (PGC-1α), GPX4, NFE2L2 (NRF2), and SIRT3 decreased with increasing disease burden, while only SIRT1 expression increased, reflecting oxidative stress and mitochondrial dysregulation. …”

Data Sheet 1_Characterizing the immune infiltrate in secondary syphilis: implications for transmission and pathology.docx by Irène Gallais Sérézal (20930579)

“…Additionally, PBMCs from healthy individuals and either primary or MyD88 knock-out keratinocytes were exposed to live Treponema pallidum cells to define initial skin responses to the bacteria.</p>Results<p>Immunohistochemistry of secondary syphilis skin lesions showed a polymorphous immune infiltrate with colocalization of T cells, B cells and antigen–presenting cells. …”

Presentation1_Impact of submarine volcanic versus hydrothermal activity onto the strontium and lithium isotopic signatures of the water column (TONGA).pdf by Valérie Chavagnac (12082001)

“…The wide range of δ⁷Li values decreases from sea-surface down to ~140 mbsl, before increasing at greater depth, while defining different linear trend according to the dissolved inorganic carbon concentrations. …”