We define the term “inhibitory reduction prowess” (IRP) as the percentage by which the product formation rate is reduced by from the initial point before inhibitor is introduced to... by J. Roadnight Sheehan (20141887)

Flow diagram illustrating the sequence of procedures executed during one time step defined as tick, each of which represents one week. by Alexandra M. Campbell (3284094)

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Data Sheet 1_Bio-functional hydrogel coated membranes to decrease T-cell exhaustion in manufacturing of CAR T-cells.docx by Aida López Ruiz (21611177)

“…To address this need, in this work, we utilized a bioinspired, scalable, tunable platform to direct T-cell activation and decrease exhaustion during CAR T production.…”

Predicting pattern diversity decreases as a function of and . by Selim Haj Ali (21222613)

Schematic representation of the main steps from gray images to the corresponding graph of the segmented regions. by Zakaria Belghali (22581967)

The standard deviation of the mean total population abundance was calculated at each time step. by Cyrine Chenaoui (22177098)

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

<b> </b> Diagram presenting the steps of process of modification and verification of the predictive equation of Work Exposure Index (WEI). FC – decrease in force capabilities, ML –... by Danuta Roman-Liu (8532645)

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

We compared the Fugl-Meyer (FMA) clinical assessment scores for individuals with stroke with their performance for each outcome measure. by Devin Sean Austin (20285144)

“…<p>FMA scores range from 0 (severe hemiparesis) to 66 (normal motor performance). We divided our individuals with stroke into subgroups based on a previously conducted cluster analysis that defined FMA > 53 as mild impairments (N = 13) and FMA < 53 as moderate to severe impairment (N = 7). …”

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

A typical metaboliser prevalence for CYP2D6 and CYP2C19 across diverse ancestry groups. These are genetically predicted based on data published by PharmGKB and CPIC. We have define... by Emma F. Magavern (20947928)

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

Convergence of the diffusion method (dataset 1). by Zakaria Belghali (22581967)

Convergence of the simulation method (transformation + diffusion). by Zakaria Belghali (22581967)