We define the term “inhibitory reduction prowess” (IRP) as the percentage by which the product formation rate is reduced by from the initial point before inhibitor is introduced to... by J. Roadnight Sheehan (20141887)

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

“…In addition, inotodiol showed to induce apoptosis, characterized by an increase in Bax expression, a decrease in Bcl-2, Bcl-XL and MCL1 expression, the initiation of cleaved PARP1 and cleaved caspase 3, and inhibition of the MAPK/ERK pathway. …”

Inotodiol decreases clone formation in HCC cells. by Yushuang Xing (20636685)

Predicting pattern diversity decreases as a function of and . by Selim Haj Ali (21222613)

IFN-γ and several PARP genes are upregulated in infected olfactory bulbs of JHMV infected mice. by Catherine M. Kerr (21492574)

PARP9 knockdown promotes apoptosis and DNA damage. by Yating Li (1819822)

“…(E) DNA damage in GC cells significantly increased post-PARP9 knockdown as determined by comet assay. (F) The anti-DNA damage capacity of GC cells decreased markedly following reduction of PARP9 expression. …”

Data Sheet 1_Imaging-based assessment of response to olaparib in platinum-sensitive relapsed ovarian cancer patients.pdf by Maria Delgado-Ortet (8840702)

“…In this work, we developed noninvasive imagingbased measurements of spatial and longitudinal heterogeneity in a retrospective analysis of a phase 2 non-randomized study of germline BRCA1/BRCA2 mutated (gBRCAm) ovarian cancer patients treated with combination of PARP inhibitors (PARPi) and immune checkpoint inhibitors (ICIs).…”

We compared the Fugl-Meyer (FMA) clinical assessment scores for individuals with stroke with their performance for each outcome measure. by Devin Sean Austin (20285144)

“…<p>FMA scores range from 0 (severe hemiparesis) to 66 (normal motor performance). We divided our individuals with stroke into subgroups based on a previously conducted cluster analysis that defined FMA > 53 as mild impairments (N = 13) and FMA < 53 as moderate to severe impairment (N = 7). …”

PARP cleavage analysis of sgCtrl and <i>IRF1</i> KO cells across conditions with and without vaccinia virus infection. by Tyron Chang (9922533)

A typical metaboliser prevalence for CYP2D6 and CYP2C19 across diverse ancestry groups. These are genetically predicted based on data published by PharmGKB and CPIC. We have define... by Emma F. Magavern (20947928)

Table 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.xlsx by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Data Sheet 1_PARP inhibition increases sensitivity to cisplatin in non-small-cell lung carcinoma via the induction of TET-dependent hydroxymethylation.pdf by Nevena Grdović (394542)

“…Treatment of A549 cells with niraparib resulted in decreased PARP activity, increased 5hmC level, and synergism with cisplatin by promoting cisplatin-induced apoptosis. …”

Figure 3 from Synergistic Effects of PARP Inhibition and Cholesterol Biosynthesis Pathway Modulation by Anna Rutkowska (19676837)

Effect of curcumin on methotrexate-induced ovarian damage and follicle reserve in rats: the role of PARP-1 and P53 by Mete Keçeci (20479508)

“…Expressions of p53 and Poly [ADP-ribose] polymerase 1 (PARP-1) increased significantly in the MTX group compared to the other groups (<i>p</i> < 0,05).…”

Over expression of SOX6 attenuates apoptosis and DNA damage in AGS cells. by Yating Li (1819822)

“…(B) At the protein level, it was confirmed that SOX6 levels decreased concomitantly with diminishing PARP9 expression. …”

Figure S1 from PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer by Li-Li Long (14963775)

Expected payoffs of <i>P</i>_<i>x</i>(<i>x</i>|<i>y</i>) in . by Hitoshi Yamamoto (738861)

“…However, there is a gap between theory and experiment in handling reputation information, with experiments often failing to capture the complexity that theoretical models propose. Here, we address two key issues: what kind of information is needed to define reputation as a social norm and the appropriate level of granularity required for reputation information to function effectively. …”

The associations of the flat ultrasonic calls with 3 other USV call types as well as with 11 behaviors recorded over early (1–3) and late (4–6) days of the light-to-dark transition... by Piotr Popik (292215)

The daily pattern of water supply head entries of pairs of rats in 10-minutes epochs. by Piotr Popik (292215)

Statistical details of data presented in Fig 16. by Piotr Popik (292215)

“…The present study shows a lights-off-induced increase in aggressive behavior but fails to demonstrate an increase in a positive affect defined by hedonic USVs. We further confirm and extend the utility of deep learning algorithms in analyzing rat social behavior and ultrasonic vocalizations.…”