Search alternatives:
latest decrease » largest decrease (Expand Search), greatest decrease (Expand Search), largest decreases (Expand Search)
marked decrease » marked increase (Expand Search)
key decrease » we decrease (Expand Search), teer decrease (Expand Search), step decrease (Expand Search)
latest decrease » largest decrease (Expand Search), greatest decrease (Expand Search), largest decreases (Expand Search)
marked decrease » marked increase (Expand Search)
key decrease » we decrease (Expand Search), teer decrease (Expand Search), step decrease (Expand Search)
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Search strategy defined by population, concept, context framework, with Boolean operators.
Published 2025Subjects: -
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Key safety measures including adverse events.
Published 2025“…As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.</p><p>Methods and findings</p><p>We conducted a multicenter, double-blind, double-dummy, randomized trial (COMET-PCOS) in participants between ages ≥18 and ≤40 years and body mass index (BMI) ≥25 kg/m<sup>2</sup> and ≤ 48 kg/m<sup>2</sup> with hyperandrogenic PCOS (defined by the Rotterdam criteria). …”
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