Showing 1 - 20 results of 5,102 for search '(( designed ((dna decrease) OR (a decrease)) ) OR ( a ((marked decrease) OR (largest decrease)) ))', query time: 0.59s Refine Results
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    Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties by Clemens Zwergel (1307868)

    Published 2025
    “…The quinoline DNMT inhibitors <b>4</b>–<b>21</b>, incorporating basic chains, were designed, synthesized, and evaluated for their ability to inhibit DNMT1 and DNMT3<i>A</i>/3L by directly measuring DNA methylation. …”
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    Study Design. by Bryan S. Margulies (21492667)

    Published 2025
    “…Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. While many cytotoxic therapies increase p21 expression as a response to DNA damage, MBC-005 increased p21 expression independent cytotoxic DNA damage. …”
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    Orthogonal experimental design. by Yining Wang (432154)

    Published 2025
    “…Fatigue test results reveal that the ZM modifier markedly extends fatigue life, with a maximum increase of 128.9%, and reduces fatigue sensitivity to the stress ratio. …”
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    Table 1_Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii.docx by Peng Wang (34436)

    Published 2025
    “…Notably, Buchnera and Arsenophonus were two dominant symbiotic bacteria related to metabolism and host adaptability in A. gossypii. The relative abundance of Buchnera in T5 and T10 significantly increased compared to M and T, while the relative abundance of Arsenophonus decreased markedly. …”
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