Showing 1 - 20 results of 5,051 for search '(( designed ((dna decrease) OR (a decrease)) ) OR ( i ((larger decrease) OR (marked decrease)) ))', query time: 0.89s Refine Results
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    Quinoline-Based DNA Methyltransferase Inhibitors Featuring Basic Side Chains: Design, Synthesis, and Insight in Biochemical and Anticancer Cell Properties by Clemens Zwergel (1307868)

    Published 2025
    “…The quinoline DNMT inhibitors <b>4</b>–<b>21</b>, incorporating basic chains, were designed, synthesized, and evaluated for their ability to inhibit DNMT1 and DNMT3<i>A</i>/3L by directly measuring DNA methylation. …”
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    <sup>1</sup>H NMR spectra for kylo-0603. by Xueqin lu (22250795)

    Published 2025
    “…Meanwhile, Kylo-0603 demonstrated a marked improvement in histological parameters, decreasing steatosis by up to 1.3 points (P < 0.001), inflammation by 1.8 points (P < 0.0001), and ballooning by 0.8 points (P < 0.01). …”
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    Table 1_Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii.docx by Peng Wang (34436)

    Published 2025
    “…Upon retransferring T1, T5, and the tenth generation of A. gossypii (T10) were retransferred to G. hirsutum (designated as T1-M, T5-M, and T10-M, respectively), the T5-M showed superior r, λ, and fecundity compared to both T1-M and T10-M. 16S rRNA sequencing and qPCR analyses indicated a significant decrease in the diversity of the symbiotic bacterial community in both T5 and T10. …”
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    Experimental design and sensor layout. by Pengcheng Li (123281)

    Published 2025
    “…Notably, the maximum deformation exhibited a direct proportionality with the stacking load, while both the deformation and its rate of reduction decreased with buried depth increased. …”
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    Study Design. by Bryan S. Margulies (21492667)

    Published 2025
    “…Intratumoral administration of MBC-005 increased survival 3.9-fold in mice and significantly decreased tumor volume 4-fold. While many cytotoxic therapies increase p21 expression as a response to DNA damage, MBC-005 increased p21 expression independent cytotoxic DNA damage. …”
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