AKT and ERK1/2 pathways are required for arsenic-inducing HIF-1α expression and angiogenesis. by Ling-Zhi Liu (20849)

“…Relative densities of p-AKT, p-ERK1/2 and HIF-1α were analyzed as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0020858#pone-0020858-g002" target="_blank">Fig. 2A</a> (right panel). *, indicates significant increase when compared with the control cells, <i>P</i><0.05. . #, indicates significant decrease when compared with the sodium arsenite treatment, <i>P</i><0.05. …”

Table_1_The Impact of COVID-19 Confinement on Tinnitus and Hearing Loss in Older Adults: Data From the LOST in Lombardia Study.DOCX by Carlotta Micaela Jarach (12203687)

“…In 2020 compared to 2019, among individuals with tinnitus, those with increasing severity (5.0%) were similar to those decreasing it (5.3%). …”

Comparison between correlations for virtual donor samples and PHHs. by Muriel M. Heldring (13020365)

“…For all fitted parameters P_i, we added a value, drawn from a normal distribution with mean 0 and standard deviation p_i ∙ c, to the parameter value. …”

Table_1_Mental Health Status of Late-Middle-Aged Adults in China During the Coronavirus Disease 2019 Pandemic.DOCX by Yong-Bo Zheng (9532996)

“…Multivariable logistic regression analyses showed that participants who were quarantined had increased odds ratios for the four mental health symptoms, and those with a good understanding of the COVID-19 pandemic displayed a decreased risk for all mental health symptoms among late-middle-aged adults. …”

Effect of BR2-PR-PPD peptides on EGF-induced cell proliferation. by Panthita Kaewjanthong (12184485)

“…The following day, the culture medium was removed. A549 were treated with EGF 50 ng/ml compared to the combination of EGF 50 ng/ml with increasing peptides (0, 0.625, 1.25 and 2.5 μM) for 24 h. …”

The cHS4 insulator block activation of Map17 but not Tal1. by Romain Desprat (73077)

“…Presence of one insulator decreases EGFP expression by more than 2-fold. Presence of 2 insulators has an even more pronounced effect. …”

Identification of TXNIP as a regulator of lactic acidosis response. by Julia Ling-Yu Chen (242650)

“…Clusters of genes whose induction and repression was most affected by TXNIP are marked and further expanded with the names of selected genes shown. (E) The effect of the control and lactic acidosis (10mM LA and 25mM LA) on the cell growth in percentage of the wild type and TXNIP deficient MEF cells.…”

MondoA is responsible for the TXNIP induction under lactic acidosis. by Julia Ling-Yu Chen (242650)

“…<p>(A) The fold of induction of normalized luciferase activities under lactic acidosis for the indicated reporter constructs driven by wild type TXNIP promoter, TXNIP promoter with the ChoRE mutated and ARRDC4 promoters. …”

Steroidogenic programme is differently regulated in the XX and XY gonads of <i>Wt1</i>^{<i>LoxP/GFP</i>}<i>;Wt1</i>^<i>Cre</i> mice. by Alejo Torres-Cano (12878169)

EspO induces CCH and cell proliferation. by Cedric N. Berger (4544008)

Data_Sheet_2_Profiling of miRNAs in Mouse Peritoneal Macrophages Responding to Echinococcus multilocularis Infection.PDF by Xiaola Guo (596236)

“…Luciferase assays showed that mmu-miR-155-5p was able to bind to the 3′ UTR of the IKBKE gene and decreased luciferase activity. Finally, we found the expression of IKBKE was significantly downregulated in both macrophages transfected with mmu-miR-155-5p and macrophages isolated from E. multilocularis-infected mice. …”

Data_Sheet_1_Profiling of miRNAs in Mouse Peritoneal Macrophages Responding to Echinococcus multilocularis Infection.PDF by Xiaola Guo (596236)

“…Luciferase assays showed that mmu-miR-155-5p was able to bind to the 3′ UTR of the IKBKE gene and decreased luciferase activity. Finally, we found the expression of IKBKE was significantly downregulated in both macrophages transfected with mmu-miR-155-5p and macrophages isolated from E. multilocularis-infected mice. …”

Image_1_Effects of Cardiomyocyte-Specific Deletion of STAT3–A Murine Model of Heart Failure With Preserved Ejection Fraction.TIF by Weilin Zhao (766615)

“…Other indicators reflecting cardiac passive stiffness and diastolic function, including end diastolic pressure volume relation, MV A value, MV E value, E/A and E/E' had different fold changes. …”

Image_2_Effects of Cardiomyocyte-Specific Deletion of STAT3–A Murine Model of Heart Failure With Preserved Ejection Fraction.TIF by Weilin Zhao (766615)

“…Other indicators reflecting cardiac passive stiffness and diastolic function, including end diastolic pressure volume relation, MV A value, MV E value, E/A and E/E' had different fold changes. …”

Image_1_Profiling of miRNAs in Mouse Peritoneal Macrophages Responding to Echinococcus multilocularis Infection.TIF by Xiaola Guo (596236)

“…Luciferase assays showed that mmu-miR-155-5p was able to bind to the 3′ UTR of the IKBKE gene and decreased luciferase activity. Finally, we found the expression of IKBKE was significantly downregulated in both macrophages transfected with mmu-miR-155-5p and macrophages isolated from E. multilocularis-infected mice. …”

Image_2_Profiling of miRNAs in Mouse Peritoneal Macrophages Responding to Echinococcus multilocularis Infection.TIF by Xiaola Guo (596236)

“…Luciferase assays showed that mmu-miR-155-5p was able to bind to the 3′ UTR of the IKBKE gene and decreased luciferase activity. Finally, we found the expression of IKBKE was significantly downregulated in both macrophages transfected with mmu-miR-155-5p and macrophages isolated from E. multilocularis-infected mice. …”

Modulating <i>E. coli</i> membrane content via co-expression of saturated and unsaturated acyl-ACP targeting thioesterases. by Rebecca M. Lennen (275606)

“…Levels of <i>fabA</i> and <i>fabB</i> were decreased in cells expressing only BTE. …”

Functional consequences of endogenous BST2 overexpression in high grade primary breast cancer cells. by Aejaz Sayeed (220486)

“…<b><i>Bottom panel</i></b> – Data plots demonstrate an increase in the number of small (4-cell) and medium (8- to 12-cell) colonies accompanied by a decrease in the number of large-sized colonies (>25-cell) in <i>BST2</i> siRNA-treated Matrigel cultures. …”

SrbB is a transcriptional regulator of genes involved in carbon metabolism, lipid metabolism, and heme biosynthesis. by Dawoon Chung (655511)

DataSheet_1_Stapled peptide PROTAC induced significantly greater anti-PD-L1 effects than inhibitor in human cervical cancer cells.docx by Yu-Ying Shi (15975992)

“…</p>Results<p>In cervical cancer celllines C33A and HeLa, the stapled peptide strongly downregulated PD-L1 to < 50% of baseline level at 0.1 μM. …”