Phenotypes associated with lifespan extension and stress resistance are observed in <i>hyl-1;lagr-1</i>. by Mai-Britt Mosbech (435186)

“…The latter displays a pronounced reduction in pumping rate and is commonly used as a genetic model for dietary restricted animals. Bars represent the mean number of pumps per minute. Compared to N2 displaying a mean pumping rate of 201±2 pumps/min, <i>hyl-1;lagr-1</i> shows a 17.4% decrease with a mean pumping rate of 166±2, P<0.0001, while <i>eat-2</i> shows a 67.2% decrease with a mean pumping rate of 66±3, P<0.0001. …”

Molecular mechanisms of impaired intestinal barrier function. by Tim Vanuytsel (513970)

“…(scale bar = 10 µm). (E) Western Blot analysis at 50 days shows decreased CLDN1 expression and a tendency towards increased CLDN2 expression (P = 0.07) in BB-DP rats (white bars) compared to controls (black bars). …”

COLXVI overexpression induces MMP9 expression. by Konstanze B. Bedal (513309)

NADH oxidase activities of recombinant gFlHb. by Edar O. Pech-Santiago (13871266)

“…<p>(A) The reaction was performed in 50 mM potassium phosphate buffer by adding 160 μM NADH at time zero, after 0.37 μM gFlHb (blue arrow) was added to reach a stable baseline with negligible spurious reaction. …”

Durability of Triple Combination Therapy Versus Stepwise Addition Therapy in Patients With New-Onset T2DM: 3-Year Follow-up of EDICT by Muhammad Abdul-Ghani (4707436)

“…Thus, the difference in HbA1c between the two treatment groups at 3 years was 0.50% (95% CI=0.39-0.61, P<0.0001). …”

Baseline characteristics. by Eiichiro Kanda (52677)

“…</p><p>Abbreviations: BMI, body mass index; eGFR, estimated glomerular filtration rate; CKD, chronic kidney disease; CVD, cardiovascular disease; outcome event, incident CKD or decrease in eGFR (>25%).…”

Palmitoylation inhibitors impair APP dimerization in CHO cells. by Raja Bhattacharyya (3359186)

“…C. Quantitation showed 54 and 58% decrease of APP-APP dimerization by cerulenin (25 μg/ml) and 2-BP (50 μM), respectively. …”

Image1_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.PNG by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

Decline in SHP2 activity follows decline in ARSB in HepG2 cells and in ARSB-null mice. by Sumit Bhattacharyya (14205)

“…<p><b>(A)</b> The SHP2 activity declined ~36% from (2.49 ± 0.15 nmol/mg protein/0.5 h to 1.59 nmol/mg protein/0.5h) following ARSB silencing (p<0.001; n = 6), and increased to 3.70 ± 0.16 nmol.mg protein/0.5h when ARSB was overexpressed in the HepG2 cells (p<0.001; n = 3). …”

Image2_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.JPEG by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

DataSheet3_Proanthocyanidins isolated from the leaves of Ficus glomerata evaluated on the activities of rumen enzymes: in vitro and in silico studies.docx by Suman Lata (369115)

“…Additionally, both compounds led to a decrease in protease activity with increasing incubation time and concentration. …”

Inhibition of PPAR-γ signaling disrupts carnitine homeostasis in ovine pulmonary arterial endothelial cells. by Shruti Sharma (308114)

“…The mRNA levels of CPT2 (E) decreased significantly whereas there was no change in CPT1 (C) and CrAT (G) mRNA levels. …”

Glucagon-like peptide 1 (GLP-1) secretion in response to oral glucose tolerance test (oGTT). by Christine Bernsmeier (237984)

“…<p><b>(A)</b> GLP-1 secretion in response to oGTT is significantly decreased in patients vs. controls (p<0.001). …”

Equilibrium binding of single strand DNA (P1) from promoter with mNdK by Praveen Kumar (8242)

“…CD spectra of P1 (4 μM) shows decrease in ellipticity at 285 nm with increasing mNdK (0–0.5 μM) in 50 mM Tris-MES-acetate pH 6.5, 1 mM MgCl, 75 mM NaCl within 30 min of incubation, after each addition, at 37°C. () Enzymatic (phosphotransfer) activity of mNdK at pH 6.5. …”

Properties of the voltage-gated sodium current from honeybee ALNs. by Aklesso Kadala (659345)

“…D, Recovery from fast inactivation in ALN (n = 12). E, Use-dependent decrease in the amplitude of the sodium current observed in an ALNs submitted to a 10-pulses train at 13 Hz. …”

fdata-01-00004-g0006_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”

fdata-01-00004-g0003_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”

fdata-01-00004-g0004_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”

fdata-01-00004-g0001_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”

fdata-01-00004-g0002_Systematic Lab Knowledge Integration for Management of Lipid Excess in High-Risk Patients: Rationale and Design of the SKIM LEAN Project.tif by Chiara Pavanello (4846771)

“…Metrics to verify the project achievements include web-site visits, the number of alerts generated, numbers of patients referred by GPs, the proportion of secondary prevention patients who achieve LDL-C <100 mg/dl or a >50% decrease from baseline.</p>…”