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point decrease » point increase (Expand Search)
nn decrease » _ decrease (Expand Search), gy decreased (Expand Search), b1 decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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20601
Table 1_Preliminary clinical activity of TP-0903 in relapsed or refractory acute myeloid leukemia with FLT3-ITD mutations.docx
Published 2025“…Three heavily treated relapsed/refractory AML patients with FLT3-ITD were treated with TP-0903 50 mg daily, on a phase 1b/2 clinical trial, for as long as disease response or clinical benefit was observed. …”
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20602
Effect of rotenone on the striatum, VTA, and SNc TH immunoreactivity.
Published 2013“…The TH immunoreactivity on the ipsilateral side of the striatum was decreased by 66.4% (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007878#pone-0007878-g004" target="_blank">Figure 4I–J</a>; *P<0.05, as compared to the contralateral side). …”
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20603
Image_1_Habenular Involvement in Response to Subcallosal Cingulate Deep Brain Stimulation for Depression.TIF
Published 2022“…Clinical response to treatment (≥50% decrease in HAMD-17 from baseline to 12 months post-operation) was significantly associated with longitudinal Hb volume change: responders tended to have increased Hb volume over time, while non-responders showed decreased Hb volume (t = 2.4, p = 0.021). …”
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20604
Data_Sheet_1_Cu5FeS4 Nanoparticles With Tunable Plasmon Resonances for Efficient Photothermal Therapy of Cancers.docx
Published 2020“…After surface modification with polyethylene glycol (PEG), the CFS nanoparticles with a plasmon resonance absorption peak at 764 nm can serve as promising photothermal agents, showing good biocompatibility and excellent photothermal performance with a photothermal conversion efficiency of up to 50.5%, and are thus used for photothermal therapy of cancers under the irradiation of an 808-nm laser. …”
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20605
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20606
Locomotor response to CNO under normal conditions.
Published 2019“…The mean number of total ambulations (± SEM) did not significantly change as a function of CNO dose, indicating that the administered doses of CNO did not elicit unforeseen locomotor effects. …”
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20607
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20608
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20609
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20610
Collagen type I monomers increase Phospho-Akt expression via PI3kinase activation.
Published 2013“…Basal, constitutive phospho-Akt expression was high in AM from each 5 healthy donors and IPF patients. A non-selective inhibitor of PI3kinase, LY294002 (50 μM, DMSO as control), abrogated CCL18 production following stimulation with collagen type I monomers and decreased significantly spontaneous CCL18 production of AM (Panel <b>B</b>). …”
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20611
Sod3 protects <i>Histoplasma</i> yeasts from ROS produced by activated macrophages.
Published 2012“…<p>(<b>A–B</b>) Survival of yeasts after infection of resting (<b>A</b>) or cytokine-activated (<b>B</b>) murine macrophages. …”
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20612
The complementary chimera IIS4I shifts the gating of Ca<sub>V</sub>1.2 channels towards low-voltage behavior.
Published 2018“…Data in graphs represent mean ± SEM. Parameter values, number of cells and statistical significance are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0193490#pone.0193490.t001" target="_blank">Table 1</a>. …”
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20613
Data Sheet 1_Treatment with pemafibrate ameliorates fatty liver index and atherogenic lipid profiles in Japanese patients with type 2 diabetes mellitus.pdf
Published 2025“…There was no significant change in hemoglobin A1c level over time. FLI (mean ± standard deviation: 68.1 ± 21.9 vs. 39.6 ± 25.0, P < 0.001), but not FIB-4 index as a marker of hepatic fibrosis (median [interquartile range]: 1.04 [0.78-1.39] vs. 1.01 [0.68-1.36], P = 0.909), was significantly decreased by treatment with pemafibrate for 12M, and the proportion of patients with metabolic dysfunction-associated SLD (MASLD) was significantly decreased from 92.3% (baseline) to 61.5% (12M).…”
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20614
Loss-of-function mutant of Mp<i>LOS1</i> displays defects in meristem maintenance.
Published 2019“…<i>p-</i>Values lower than 0.01 were indicated by asterisks (*). (E-G) Cell division activities in Mp<i>los1-1</i> mutants decreased after 3 days’ incubation. …”
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20615
Mutation of the hydrophobic tip residues disrupts evoked transmitter release.
Published 2020“…<p>The single hydrophobic mutation decreased neurotransmitter release by 50% while the double mutation inhibited release to a greater extent than that seen in <i>syt<sup>null</sup></i> mutants. …”
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20616
Comparison of whole genome prediction accuracy across generations using parametric and semi parametric methods
Published 2021“…The genome comprised one chromosome of 100 cM length carrying 50 QTLs. There was no significant difference between accuracy of investigated methods (p > 0.05) but among three methods, the highest mean accuracy (0.659) was observed for BayesA. …”
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20617
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20618
TLR4 and NF-κB signaling pathway is required for the reduction of let-7b expression in response to <i>H.pylori</i> infection.
Published 2013“…<p>(A) TKA-242 (1 uM) decreased the expression of TLR4 protein in AGS and GES-1 cells with <i>H.pylori</i>-infection. …”
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20619
SOCS3 regulated the fate of HSCs.
Published 2015“…Bar = 50 μm. (B) BFU-E and CFU-E derived from shSOCS3-1 CD34<sup>+</sup> cells. …”
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20620
Mechanism of SFK phosphorylation and negative regulation of PKA in chicken sperm.
Published 2020“…<p>Sperm were incubated with 0–50 μM H-89 (PKA inhibitor), 25 μM KH7 (sAC inhibitor), 50 μM MDL (tmAC inhibitor), 0–250 μM PTP inhibitor, or EGTA-AM in the presence or absence of SKI606 and SU6656 and then subjected to immunodetection for p-SFK-Y416 or p-PKAs. …”