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fold decrease » fold increase (Expand Search), fold increased (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
w decrease » we decrease (Expand Search), _ decrease (Expand Search), _ decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
e fold » 5 fold (Expand Search), _ fold (Expand Search), 2 fold (Expand Search)
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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…<i>p</i> > 0.05, Student’s <i>t</i> test. <b>(M)</b> Median fold-change (ether/ctrl) of protein levels in the following subsets of Hsp90 clients (left to right): All clients (<i>n</i> = 280), Hsp90 w/o Trx or Ubx targets (<i>n</i> = 197), Hsp90 and Trx but not Ubx targets (<i>n</i> = 52), Hsp90 and Trx targets (<i>n</i> = 69), Hsp90 and Ubx targets (<i>n</i> = 31), Hsp90 and Trx and Ubx targets (<i>n</i> = 16). …”
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FTY720 decreased viability, proliferation, and motility and induced apoptosis in human hepatoblastoma cells.
Published 2019“…(B) Following 24 hours of treatment with FTY720, the proliferation of HuH6 cells measured using the CellTiter 96 cell proliferation assay was significantly decreased (IC<sub>50</sub> = 6.4 μM, p ≤ 0.05). (C) HuH6 cells were plated and allowed to reach 80% confluence, at which time the media was changed for fresh media (0, 5, or 8 μM FTY720) and a standard scratch wound was made. …”
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