Computational and Experimental Investigation of Li-Doped Ionic Liquid Electrolytes: [pyr14][TFSI], [pyr13][FSI], and [EMIM][BF₄] by Justin B. Haskins (1745515)

“…While the diffusion exhibits a systematic decrease with increasing <i>x</i>_Li⁺, the contribution of Li⁺ to ionic conductivity increases until reaching a saturation doping level of <i>x</i>_Li⁺ = 0.10. …”

EGFR inhibitor differentially modulates the expression of antigen presenting molecules and PD-L1 on HaCaT cells. by Jin S. Im (234975)

“…(B) HaCaT cells were treated with IFNγ at different concentrations ranging 1 pg/ml to 1000 pg/ml in the presence or absence of erlotinib at concentration of 10 μM for 24 hours, and assessed for surface expression of MHC-I, MHC-II, and PD-L1 in Mean Fluorescence Intensity (MFI). While the expression of MHC-I and MHC-II on HaCaT cells was further up-regulated in the presence of erlotinib and IFNγ at all dose range tested for MHC-I and at a greater than 1pg/ml for MHC-II compared to IFNγ alone, IFNγ induced overexpression of PD-L1 was abrogated by the addition of erlotinib to IFNγ at a greater than 100 pg/ml. …”

BPLF1 deubiquitinates TOP2 and stabilizes TOP2ccs. by Jinlin Li (2267896)

“…Clearance was calculated as 1- (intensity of the smears after treatment for 4 h/intensity of the smears after treatment for 30 min) x100. Treatment with MG132 reduced the clearance of TOP2ccs in BPLF1 negative cells and a similar reduction was achieved by expression of BPLF1 in Dox treated cells. …”

DataSheet_1_Differential Effects of Purinergic Signaling in Gastric Cancer-Derived Cells Through P2Y and P2X Receptors.pdf by María José Hevia (6833402)

“…Finally, in tumor-derived biopsies, we found an increase of P2Y₂R and a decrease in P2X4R expression; however, we found high variability between seven different biopsies and their respective adjacent healthy gastric mucosa. …”

Microarray analysis of endoxifen concentration-dependent changes in gene expression in the presence of estrogen and physiologically relevant levels tamoxifen and its metabolites. by John R. Hawse (227611)

“…<p> (<b>A</b>) Venn diagram of genes whose expression levels were significantly altered by 1.5 fold or greater in MCF7 cells treated with 10 nM estrogen (E₂), 300 nM tamoxifen (TAM), 7 nM 4-hydroxy-tamoxifen (4HT) and 700 nM N-desmethyl-tamoxifen (NDT), plus indicated concentrations of endoxifen, relative to cells treated with all compounds minus endoxifen for 24 hours. …”

The governing learning rule in cultured neural networks. by Takuya Isomura (839119)

“…<b>(C)</b> Measured changes in connection strengths and those estimated from Hebbian and state-dependent Hebbian plasticity rules. Black bars are the mean ± S.E.M of the change (trial 100 –trial 1) in <i>W</i>₁₁ and <i>W</i>₂₂ (<i>n</i> = 46 from 23 cultures), which increased in all cases (****, <i>p</i> < 10⁻⁵). …”

Stochastic trajectories at cell and tissue scale. by Michael Alexander Ramirez Sierra (20209354)

“…Statistics are computed from a batch of 1000 simulations of a 100-cell tissue system.…”

Table 1_The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections.pdf by Guoqian Ma (22253182)

“…</p>Results<p>Between 1990 and 2021, global AA-related deaths rose by 73.9% [from 79,608 (95% UI, 74,398–84,032) to 138,450 (123,754–149,214)], while the mortality rate declined by 21.4% (from 11.86 to 9.32 per 100,000). Similar patterns were observed for DALYs, with a 62.6% increase in total DALYs but a 26.5% decrease in rates. …”

Study flow and included patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Table 2_The global burden of aortic aneurysm in adults over 55: evolving trends, risk factors, and projections.pdf by Guoqian Ma (22253182)

“…</p>Results<p>Between 1990 and 2021, global AA-related deaths rose by 73.9% [from 79,608 (95% UI, 74,398–84,032) to 138,450 (123,754–149,214)], while the mortality rate declined by 21.4% (from 11.86 to 9.32 per 100,000). Similar patterns were observed for DALYs, with a 62.6% increase in total DALYs but a 26.5% decrease in rates. …”

Weaning parameters before planned extubation. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Prenatal Air Pollution Exposure and Early Cardiovascular Phenotypes in Young Adults by Carrie V. Breton (74382)

“…Prenatal PM₁₀ and PM_2.5 exposures were associated with increased CAS. For example, a 2 SD increase in prenatal PM_2.5 was associated with CAS indices, including a 5% increase (β = 1.05, 95% CI 1.00–1.10) in carotid stiffness index beta, a 5% increase (β = 1.05, 95% CI 1.01–1.10) in Young’s elastic modulus and a 5% decrease (β = 0.95, 95% CI 0.91–0.99) in distensibility. …”

Supplementary Material for: Neuronal Nitric Oxide Synthase Inhibition Prevents Cerebral Palsy following Hypoxia-Ischemia in Fetal Rabbits: Comparison between JI-8 and 7-Nitroindazo... by Yu L. (3691228)

“…JI-8 was also significantly superior to saline in preserving smell, muscle tone and righting reflex function, but 7-NI did not show significant improvement. Furthermore, a 100-fold increase in the dose (15.75 µmol/kg) of 7-NI significantly decreased systolic blood pressure in the dam, while JI-8 did not. …”

S1 Data - by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

Baseline characteristics of enrolled patients. by Chung-Yeh Chuang (15285925)

“…In the multivariate analysis, being underweight (adjust OR [aOR], 3.80, compared to normoweight; 95% CI, 1.23–11.7) and lower maximal inspiratory airway pressure (aOR per one cmH₂O decrease, 1.05; 95% CI 1.00–1.09) remained significantly associated with extubation failure.…”

MLN4924 regulates NSs-dependent early PKR activation in RVFV-infected cells. by Rajini Mudhasani (619683)

“…The data derived from MLN4924 treated cells was normalized with the corresponding DMSO treated controls (average infection rates are indicated under the bar graph), which were considered as 100% and expressed as the mean ± SD. The inset shows a decrease in PKR expression levels in PKR siRNA transfected cells by Western blot analysis. …”

The mRNA and protein levels of Vasohibin-1, renal hypertrophy, creatinine clearance and urinary albumin excretion. by Norikazu Hinamoto (575811)

“…Real-time PCR and immunoblot analysis showed a substantial decrease in the VASH1 mRNA and protein expression in the kidneys in the VASH1^+/− mice compared with the wild-type mice. …”

Minimal photobleaching of mbYFPQS occurs with repeated photo-stimulation. by Spencer D. Watts (327115)

“…<p>A. A cultured midbrain neuron expressing mbYFPQS was imaged with an exposure of 100 ms every 5 s for 35 min with less than 6% decrease in baseline fluorescence. …”

File S1 - The Capacity of Red Blood Cells to Reduce Nitrite Determines Nitric Oxide Generation under Hypoxic Conditions by Marcel H. Fens (595238)

“…When comparing commercial hemoglobin with concentrations of 4, 8, 12 and 16 g/dL, incubated with 5 mM nitrite under strict hypoxia, a concentration-dependent effect was seen alike we have seen for hemolysates (C, D and E). …”

Cellular characteristics of <i>M</i>. <i>commoda</i> during short-exposure light shift experiments and qPCR analysis of three genes. by Marie L. Cuvelier (3825829)

“…<p>Percent change in (A) mean normalized FALS cell^-1 and (B) mean bead normalized red fluorescence for controls and the HL and HL+UV treatments. …”