Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Distribution of final population size (A) and mean change in mean MSI over time (B) over 100 simulations for each parameter set shown in Table 3 in the absence of weevils (left) an... by Alexandra M. Campbell (3284094)

Decreased peritumoral myofibroblasts in the MC38 S.C. tumors of <i>S100a4-Cre; Ext1</i>^<i>f/f</i> mice. by Ayumi Niwa (6256790)

Experimental validation revealed that ACADSB and ACADM decreased in patients with UC. by Hongliang Chen (538815)

The effects of NAC on the decreased number of myotube formations caused by arecoline. by Yi-Xuan Li (6633845)

Loss of FOXP1 results in decreased number of bRGCs. by Seon Hye E. Park (16765033)

PGRN decreased Dectin-2 expression on the surface of macrophages and neutrophils. by Jiayu Liu (3951515)

Means and 95% confidence interval (CI) of all costs, benefits, and the difference in net benefits from the probabilistic reference case given in 2019 USD for 3 years for a 100-cow... by Marlena Waldbauer (18291223)

Coupled negative feedback decreases the overall LG. by Rong Gao (476219)

Changes in mean modeled Zn, Pb, and Cd concentrations in <i>Hylocomium splendens</i> between 2001 and 2017. by Peter N. Neitlich (4034300)

Sales-weighted mean salt content (g/100 g) by category and year. by Lauren K. Bandy (10912766)

Subjects:

Average mean decrease Gini across 100 partitions for the top 10 most important variables for binary mixed model and random forest. by Helal El-Zaatari (20442243)

“…<p>Average mean decrease Gini across 100 partitions for the top 10 most important variables for binary mixed model and random forest.…”

Means for STEM competence for pre- and post-test. by Esther Kim (2996622)

“…After the Challenge, participants increased in awareness of global issues, and engagement with others, but also showed a small but significant decrease in respect for people from other cultural backgrounds. …”

Intensity-modulated proton therapy decreases dose to organs at risk in low-grade glioma patients: results of a multicentric <i>in silico</i> ROCOCO trial by Daniëlle B. P. Eekers (5560430)

Locations, climate conditions (shown as the mean for 1990–2012, as obtained from the China meteorological sharing service system (http://cdc.cma.gov.cn/)), and the initial surficia... by Weiwei Zhang (222964)

MVEC microvessel formation is restricted in hydrogels exhibiting increased stiffness or decreased concentration of adhesive peptides. by Rebecca A. Scott (488956)

“…(<b>L</b>) Tubule diameter on day 14 significantly increased with increasing RGD concentration. In <b>A, C-G, I-L</b>: data are represented as the mean ± SEM, with <i>n</i> = 3 biological replicates per condition. …”

Decrease in the interscale differentiation marker in senescence prone SAMP8 mice. by Gopakumar Changarathil (3479078)

Exploration of the connected interface (S100A1/MDM2) section in S100A1. by Deepu Dowarha (5673440)

Subjects:

The brain’s GS fluctuation (standard deviation of GS) decreases with time of day. by Csaba Orban (8462997)