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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”
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Knockdown of AR expression decreases the efficiency of KSHV infection in endothelial cells.
Published 2017“…<p>(a) Endogenous AR expression in HUVECs and SLK cells is efficiently impaired by RNA interference of the AR. siRNAs were transfected into cells at final concentrations of 100 nM for HUVECs and 200 nM for SLK cells using Lipofectamine 2000. …”
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Results of western blots showing the protein levels in different brain structures.
Published 2017Subjects: -
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The Site×Sex interaction for mean N100 amplitude to the “decrease” instructional set.
Published 2013“…<p>The Site×Sex interaction for mean N100 amplitude to the “decrease” instructional set.…”
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Downregulation of activin A leads to a decrease in proliferation.
Published 2015“…Knockdown of activin A significantly decreased proliferation (E), enhancing the number of cells at G0/G1 and reducing the number in the S phase of cell cycle (F). …”
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