Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

S100a9 Knockdown Decreases the Memory Impairment and the Neuropathology in Tg2576 Mice, AD Animal Model by Tae-Young Ha (254769)

Subjects:

Map of spatial GPoE folds and predictive ability by fold. by Forrest Li (21512582)

“…<p>Correlations between genetics and environment are demonstrated through prediction but decrease when considering spatial distance. <b>A)</b> Map of sampled cross-validation folds used in spatial GPoE. …”

RA increases S100β+ and decreases peripherin+ cell prevalence while EDN3 decreases S100β+ cell prevalence. by Jonathan M. Gisser (456149)

“…(A) The proportion of S100β+ cells was enriched by RA and decreased in response to EDN3 (B) RA increased, and EDN3 decreased the fraction of proliferating S100β+ cells. …”

Heat map showing time dependent changes for all genes with a ≥ 2-fold maximal increase or decrease in gene expression (mRNA) in response to single doses of IFN-γ. by Daniel R. Ambruso (12042605)

S100A9 Knockout Decreases the Memory Impairment and Neuropathology in Crossbreed Mice of Tg2576 and S100A9 Knockout Mice Model by Hee Jin Kim (469168)

Subjects:

S100A7 downregulation decreases osteolytic lesions <i>in vivo.</i> by Vikram Paruchuri (87721)

Effect of VEGF121 or VEGF165 on the cell shape and F-actin structure in TM cells. by Tomokazu Fujimoto (709192)

Effect of VEGF121 or VEGF165 on cell shape, F-actin structure, and junctional proteins in SCE cells. by Tomokazu Fujimoto (709192)

Loss of MMP7 leads to a decrease in transformation in cells lacking PKP3. by Srikanta Basu (721886)

The rate of lariat formation is decreased two-fold by isoginkgetin treatment. by Jesse M. Gray (527662)

“…Error bars in (A, C) represent s.e.m. from three biological replicates.</p>…”

TGFβ1 expression was increased, and RASAL1 expression was decreased in NTM cells in response to a hypoxic environment. by Fiona McDonnell (2636635)

“…</b> After 24 hours, RASAL1 was decreased; fold change 0.51+/-0.13 (P<0.05). <b>C.</b> Western blotting shows an apparent increase in TGFβ1 after 6 hours. …”

Confocal images presenting the phenotypes of S100A6-immunopositive cells in the ARH. by Katarzyna Bartkowska (453261)

Subjects:

Confocal images of the SVZ and the DG. by Katarzyna Bartkowska (453261)

Subjects:

Representative immunofluorescence images for S100A6 in brainstem structures in control and stressed mice. by Katarzyna Bartkowska (453261)

Subjects:

Results of western blots showing the protein levels in different brain structures. by Katarzyna Bartkowska (453261)

Subjects:

Confocal images presenting the phenotypes of S100A6-immunopositive cells in the SVZ. by Katarzyna Bartkowska (453261)

Subjects:

Confocal images of brain sections immunostained with S100A6 and vimentin antibodies. by Katarzyna Bartkowska (453261)

Subjects:

Representative immunofluorescence images for S100A6 in some brain structures related to stress responses. by Katarzyna Bartkowska (453261)

Subjects: