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Binding of <i>PC3/Tis21</i> to the <i>Id3</i> promoter and corresponding decrease of <i>Id3</i> mRNA.
Published 2009“…<p>(<b>A–D</b>) A PC12 cell line carrying an inducible <i>PC3</i> (rat) cDNA under control of the tet-off system (i.e., a tetracycline responsive element TRE-PC3, activated by a tetracycline-regulated transactivator, CMV-tTA, in the absence of doxycycline) was used to analyze the binding of <i>PC3</i> to the <i>Id3</i> promoter, by chromatin immunoprecipitation (ChIP). …”
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Neural responses to corner-folds depend on corner angle.
Published 2019“…Blue points represent responses from individual V1 neurons to corner-folds of three different angles (S90°, S52° and S40°) and to the non-corner gradient (P180°). …”
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The I827K substitution destabilizes the 3D fold of E6AP<sup>C-lobe</sup> (residues 761–875).
Published 2020“…<p>(A) The assigned <sup>1</sup>H-<sup>15</sup>N-HSQC spectrum of 3.5 mM human E6AP catalytic C-lobe (residues 761–875) using the one-letter amino acid code and residue number according to the human E6AP sequence. …”
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Chemokines, with the exception of CXCL1 and MCP-1, decrease acutely following 5 Gy IR.
Published 2024Subjects: -
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sC5b-9 patients decrease in patients treated with mycophenolate mofetil.
Published 2015“…When analyzed separately based upon treatment, the decrease in sC5b-9 levels was due to a decrease in patients treated with mycophenolate mofetil (P < 0.001 by linear regression; n = 12 for all time-points). …”
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MK-STYX decreases RhoA activation.
Published 2014“…<p>(<b>A</b>) PC12 cells were transfected with pMT2 or pMT2-FLAG-MK-STYX-FLAG. 24 hr post-transfection cells were stimulated with 100 ng/ml NGF, and lysed at the indicated time points. …”
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UNC-62 RNAi decreases expression of collagen genes and increases expression of intestinal genes.
Published 2013“…The histogram indicates the distribution of genes by average fold-change upon <i>unc-62</i> RNAi. For 1699 genes with intestine-enriched expression <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-McGhee1" target="_blank">[23]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Pauli1" target="_blank">[33]</a>, <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Spencer1" target="_blank">[34]</a> as well as the subset of 291 genes that also decrease expression with age <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1003325#pgen.1003325-Budovskaya1" target="_blank">[10]</a>, we determined the average mean-centered fold-change from triplicate RNA-seq experiments of <i>unc-62</i> RNAi as compared to controls. …”
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<i>S.</i> Typhimurium-infected mice have tissue inflammation and thrombosis, increased hematopoiesis, and decreased splenic iron.
Published 2013“…(B) Mouse spleen, 3 weeks post-infection; extramedullary hematopoiesis (EMH; arrow, megakaryocytes), histiocytic infiltration (I) throughout the red pulp, and thrombus (T). H&E stain (A, B). (C) Spleen, mock-infected (left) and infected mouse (right), 3 weeks post-infection; markedly decreased ferric iron staining in red pulp. …”
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