Breast Cancer 1 (BrCa1) May Be behind Decreased Lipogenesis in Adipose Tissue from Obese Subjects by Francisco J. Ortega (161440)

“…Consistent with its role limiting fatty acid biosynthesis, both <em>BrCa1</em> mRNA (3.5-fold, p<0.0001) and protein (1.2-fold, p = 0.001) were increased in pre-adipocytes, and decreased during <em>in vitro</em> adipogenesis, while P-ACC decreased during differentiation of human adipocytes (p = 0.005) allowing lipid biosynthesis. …”

Rdh10a deficient embryos have decreased expression of RA signaling responsive genes. by Enrico D’Aniello (798447)

“…<p>(A-F) ISH for <i>cyp26a1</i>, <i>hoxb5b</i>, <i>and dhrs3a</i> expression in control sibling and Rdh10a deficient embryos. …”

L1 animals lacking <i>adr-2</i> have decreased expression of genes regulated by insulin signaling. by Ananya Mahapatra (17041557)

Behavior of split^<50cM <i>ClvR</i> V2 with linkage. by Georg Oberhofer (3401438)

“…<p>Incorporating linkage into split <i>ClvR</i> (split^<50cM <i>ClvR</i> V2) results in a graded increase in drive strength, and duration of <i>Rescue</i>/Cargo/gRNAs at high frequency, as the degree of linkage increases (map distance decreases). …”

Behavior of split^<50cM <i>ClvR</i> V1 with linkage. by Georg Oberhofer (3401438)

Chemical inhibition of formins decreases actin pedestal assembly by EPEC, but not by KC12+EspF_U. by Katrina B. Velle (4330957)

a-c: Bone marrow (BM) HIF2 α is inappropriately decreased in uremic anemia. by Daniel Landau (440830)

“…<p>BM HIF2 α protein (depicted as percentage of actin-corrected concentration) increases in 7 day-bled rats (Fig 2a) Vs control. Contrary to that, BM HIF2 α protein decreases in uremic (4 weeks after 5/6 nephrectomy) rats (Fig. 2b). …”

Uncoupling protein-2 is an antioxidant that is up-regulated in the enamel organ of fluoride-treated rats by Maiko Suzuki (8794223)

“…Maturation stage incisor enamel organs (EO) were harvested from F⁻-treated rats and mice were assessed to determine if vitamin E ameliorates dental fluorosis. Uncoupling protein-2 (<i>Ucp2</i>) was significantly up-regulated by F⁻ (∼1.5 & 2.0 fold for the 50 or 100 ppm F⁻ treatment groups, respectively). …”

Decreased expression of key regulators of the transition from proliferation to prehypertrophy in chondrocytes in the absence of <i>c-Myc</i> deletion. by Zi-Qiang Zhou (225011)

CD5-2 decreases established CCM lesions in the hindbrain of <i>Ccm2</i>^<i>ECKO</i> mice and lesions in the retina of <i>Ccm2</i>^<i>ECKO</i> mice. by Jia Li (160557)

Comparison of DRM subunit chromatin localization in wild-type and <i>lin-35</i> null late embryos. by Paul D. Goetsch (4559587)

“…H3K4me3 ChIP was included as a positive control. Signals are presented as the log₂ fold enrichment of the ChIP signal for each region vs. a negative control region (a non-coding region of chromosome IV). …”

The position of the mutations I989T, V992M and V997M in the ACE C domain. by Olga V. Kryukova (19819428)

Reduction of Tks5 expression in tumor cells is associated with decreased angiogenesis. by Barbara Blouw (715467)

Spinal cord of CCI-mice treated with EGCG and compound 30 at 14 dpi showed decreased levels of inflammatory cytokines by Xavier Xifró (719821)

Fig 5 - by Marian Adan (16641634)

<i>Ex vivo</i> deletion of <i>sirt1</i> decreases expression of RUNX2 downstream targets. by Kayvan Zainabadi (502381)

“…<b>C)</b> While SIRT1 knockout osteoblasts (Cre) express comparable amounts of Runx2, they show a near two-fold reduction in the expression of the Runx2 downstream target, <u>Osterix</u> (Osx). …”

Absence of neocortex is associated with a dorsal shift of piriform cortex in <i>Emx1</i>-cKO mice. by Sathish Venkataramanappa (10331993)

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-6 by Mrigank Srivastava (94935)

“…Data represent at least 3–5 independent experiments. (F-I), immunohistochemistry of cath K protein in lung tissue of wild-type mice (F, H) or cath K tg mice (G, I). …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-0 by Mrigank Srivastava (94935)

“…Data represent at least 3–5 independent experiments. (F-I), immunohistochemistry of cath K protein in lung tissue of wild-type mice (F, H) or cath K tg mice (G, I). …”

ChAT knock-down using an antisense oligodeoxynucleotide (AS-ODN) against ChAT, and decreased expression of ChAT in the DRG and spinal cord by Misaki Matsumoto (52354)