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66121
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66122
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66123
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66124
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66125
Relationship between calcitriol and GDNF signaling.
Published 2013“…(A, B) 10 nM calcitriol added to media caused almost a 1.8-fold increase in GDNF expression, observed by Western blotting. …”
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66126
The NH<sub>2</sub>-terminus of PDX-1 binds to <i>Krt19</i> promoter DNA.
Published 2010“…C) MIN6 cells were transfected with V5-tagged full length PDX-1 or PDX-1 Δ1-37. DNA precipitation was carried out as described above, and membranes were probed with anti-V5. …”
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66127
siRNA screening system to identify regulators of insulin promoter activity.
Published 2012“…If the siRNA targets a positive regulator, GFP/mCherry MFI decreases. …”
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66128
Induced Wnt signaling post-SE coordinates AMPK and mTOR signaling pathways.
Published 2021“…(n = 3–5 for each group). Data are represented as mean ± SEM. …”
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66129
Data_Sheet_1_SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine.doc
Published 2018“…Levels of the ubiquitin-proteasome system (UPS)-related makers ubiquitin (Ub) and UbE1, as well as the autophagy-lysosome pathway (ALP)-related markers LC3, P62 and lysosomal associated membrane protein 2A (LAMP2A), were also measured in SH-SY5Y cells transfected with lentivirus and mice injected with adenovirus. …”
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66130
Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP)
Published 2011“…Using Nexus software analysis we combined the array-CGH data with data from gene expression profilings and identified genes that were altered in both inputs. A subset of genes identified as downregulated (<em>ALDH1A3</em>, <em>ANXA1</em>, <em>TLR4</em> and <em>RAB5A</em>) or upregulated (<em>COX6A1</em>, <em>NFIX</em>, <em>ME1</em>, <em>MAPK</em> and <em>TAP2</em>) were validated by siRNA in the tolerant or parental cells to alter sensitivity to PPP and confirmed to alter sensitivity to PPP in further cell lines.…”
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66131
Metabolomics raw data and table of extracted peak areas for BT478, BT530 and NHA cells cultured in the presence of MPA, Compound 3 (IC80) or vehicle control, for 6 hours.
Published 2024“…The linear gradient employed was as follows: 0–2.5 min 99% A, 2.5–7.5 min decrease to 80% A, 7.5–13 min to 55% B 652 and finally 13–15 min to 99% B and held for 1 min. …”
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66132
Table_1_Regulation of miRNA expression in the prefrontal cortex by fecal microbiota transplantation in anxiety-like mice.docx
Published 2024“…MiRNA analysis identified five key miRNAs affecting GAD pathogenesis, including mmu-miR-10a-5p, mmu-miR-1224-5p, mmu-miR-218-5p, mmu-miR-10b-5p, and mmu-miR-488-3p. …”
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66133
DataSheet_1_Differences in Prostate Cancer Incidence and Mortality in Lower Saxony (Germany) and Groningen Province (Netherlands): Potential Impact of Prostate-Specific Antigen Tes...
Published 2021“…Trends in age-standardized incidence rates (ASIR) and mortality rates (ASMR) for specific age groups were assessed using joinpoint regression.</p>Results<p>The mean annual PCa ASIR between 2003 and 2012 was on average 19.9% higher in Lower Saxony than in Groningen (120.5 vs. 100.5 per 100,000), while the mean annual ASMR was on average 24.3% lower in Lower Saxony than in Groningen (21.5 vs. 28.4 per 100,000). …”
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66134
The STIM2-TM domain activates the cytosolic region of STIMs less efficiently than that of STIM1.
Published 2018“…Left: average time course of whole-cell I<sub>CRAC</sub> currents measured at –100 mV. Currents mediated by STIM1121-ΔK developed significantly more slowly than control (time to peak, 72 ± 7 s versus 147 ± 9 s, <i>n</i> = 7, ****<i>P</i> < 0.0001, <i>t</i> test), with the maximal current density also reduced (–5.5 ± 0.8 pA/pF versus –1.5 ± 0.1 pA/pF, <i>n</i> = 7, *****<i>P</i> < 0.0004, <i>t</i> test). …”
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66135
Effects of therapeutic and aerobic exercise programs in temporomandibular disorder-associated headaches
Published 2022“…Methodology Thirty-six patients diagnosed with headache attributed to TMD participated in the study and were divided into three groups of 12 patients: a therapeutic exercise program (G1, mean age: 26.3±5.6 years), a therapeutic and aerobic exercise program (G2, mean age: 26.0±4.6 years), and an aerobic exercise program (G3, 25.8±2.94 years). …”
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66136
SB-216763 inhibits the GSK-3 pathway.
Published 2013“…<p><b>A</b>) Representative images of western blots for phospho-GSK-3ß, phospho-LRP6, phospho-ß-Catenin, phospho-Akt, and phospho-ERK in response to i.p. injection of SB-216763 (2.5 and 5.0 mg/kg) or vehicle (0 mg/kg) (n = 3/group). …”
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66137
Effects of cannabinoid receptor antagonism on pancreatic stellate cells.
Published 2013“…<p>(A) MTT assays after 48 hours' incubation of PSC with graded concentrations of CB1- and CB2-receptor antagonists AM251 and AM630 (p = n.s. for concentrations of 1.25, 2.5 and 5 µM). …”
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66138
Altered Responses to Homeostatic Cytokines in Patients with Idiopathic CD4 Lymphocytopenia
Published 2013“…The induction of phospho-STAT5 after IL-7 stimulation was decreased in memory CD4<sup>+</sup> T cells of some ICL patients, which correlated with a decreased expression of the IL-7Rα receptor chain (R = 0.74, p<0.005) and with lower CD4<sup>+</sup> T cell counts (R = 0.69, p<0.005). …”
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66139
Silibinin and SIL inhibit HCVpp-mediated fusion.
Published 2013“…After a 2 min-equilibration, lipid mixing was initiated by decreasing the pH to 5.0 with diluted HCl, and R<sub>18</sub> dequenching was recorded. …”
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66140
Building Strain with Large Macrocycles and Using It To Tune the Thermal Half-Lives of Hydrazone Photochromes
Published 2018“…Strain has been used as a tool to modulate the reactivity (e.g., mechanochemistry) and thermal isomerization kinetics of photochromic compounds. …”