Simplified Insulin-like growth factor 1 receptor (IGF1R) and mTORC1 and mTORC2 signaling in relation with EWS-FLI1. by Vivek Subbiah (353745)

“…Now mTORC1 complex (mTOR + mLST8+Raptor) is activated by GTP-bound Rheb and phosphorylates proteins like S6K. This starts a negative feedback loop to modulate auto-activity, through S6K-mediated pathway decrease in the activation of PI3K. …”

Dietary lysine requirement of adult lambari ( Astyanax altiparanae ) (Garutti and Britski, 2000) by Daniel Abreu Vasconcelos Campelo (5839391)

“…Fish fed 12.13 to 19.92 g kg−1 lysine showed increased weight gain and percent weight gain, and fish from those treatments also showed improvement in final carcass quality by a decrease in whole-body lipid content. Fish fed 12.13 g kg−1 lysine showed lower ALT and AST activities in blood serum when compared with fish fed the highest lysine levels. …”

Data_Sheet_1_Knockdown of NRSF Alleviates Ischemic Brain Injury and Microvasculature Defects in Diabetic MCAO Mice.PDF by Cheng-Feng He (12540442)

“…We found that diabetes enhanced the MCAO-induced elevation of NRSF in the hippocampus in accompany with an elevation of its corepressors, HDAC1, and mSin3A, and decrease of β-TrCP. By using histological/immunofluorescence staining and neurobehavioral testing, our results showed that the brain damage and learning/memory impairment were aggravated in diabetic ischemic mice but significantly attenuated after stereotaxic injection of NRSF-shRNA. …”

Cytotoxicity, and antimicrobial and physicochemical properties of sealers incorporated with Uncaria tomentosa by Nathália Lima CALDAS (12656245)

“…The incorporation of UT was associated with a decrease in flow, for both sealers, an increase in AH Plus setting time, increase in MTA Fillapex pH values, and solubility (after 14 days), for both sealers (p < 0.05). …”

Reduction of organelle motility by removal of potassium and other solutes by John W. Murray (2841077)

“…However, extracellular flux analysis showed near normal mitochondrial oxygen consumption and only a small decrease in extracellular acidification, the latter suggesting decreased glycolysis or proton efflux. …”

Image_2_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…Introduction<p>Extracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. …”

Evaluation of the physical, chemical and mechanical properties of starch/PVA/bentonite clay films modified with glycidyl methacrylate by Alberto Gonçalves Vieira de Carvalho Neto (10472190)

“…This strategy also resulted in a 25% improvement in tensile strength, maintaining the same Young’s modulus and slight decrease in thermal stability (onset of degradation 14 ° C lower). …”

Table 1_Antimicrobial susceptibility profiles of commensal Clostridium perfringens isolates from chickens in Hungarian poultry farms between 2022 and 2023.docx by Ádám Kerek (14263613)

“…</p>Results<p>Our findings revealed a decrease in the efficacy of penicillin-based antibiotics, which are primary choices for treating C. perfringens-related infections, with resistance observed in 48.3% of isolates for penicillin and 20.7% for amoxicillin. …”

3BrP effect on glycolytic enzymes as well as on differentiation markers assessed via embryoid body (EB) formation. by Ana Sofia Rodrigues (491559)

“…Results were normalized to beta-Actin protein levels and are represented as percentage relative to the control; the results represent n = 4. Right: a representative blot demonstrating the decrease in protein levels for glycolytic enzymes. …”

Polyheteroaryl Oxazole/Pyridine-Based Compounds Selected in Vitro as G‑Quadruplex Ligands Inhibit Rock Kinase and Exhibit Antiproliferative Activity by Daniela Verga (2202436)

“…Herein, we report on the synthesis of parent compounds bearing either amino side chains (TOxaPy-1–5) or featuring an isomeric oxazole-pyridine central connectivity (iso-TOxapy, iso-TOxapy 1–3) or a bipyridine core (iso-TOxabiPy). …”

Data Sheet 1_Study on the function of TTG1 gene in Camellia oleifera.docx by Chengcheng Xiang (5512442)

“…In this study, we isolated the CoTTG1 gene from C. oleifera, which encodes a nuclear-localized protein (molecular weight 38.38 kDa, pI 5.0) sharing 99.71% sequence identity with Camellia japonica TTG1. …”

Table1_Towards attractive texture modified foods with increased fiber content for dysphagia via 3D printing and 3D scanning.docx by Astrid Ahlinder (7465667)

“…The resulting formulation has improved nutritional properties, while remaining suitable for constructing visually appealing meals, as demonstrated by 3Dprinting a chicken drumstick from a model generated with 3D scanning.…”

Characterization of <i>ob/ob</i>-luc mice. by Manishkumar Patel (627143)

“…<p>A) Weight increases significantly with age in <i>ob/ob</i>-luc mice consistent with the original <i>ob/ob</i> mouse model on the B6 black background. …”

Data_Sheet_1_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.PDF by Yan Shi (166398)

“…However, potato production is affected by numerous biotic and abiotic stresses, among which Fusarium dry rot is a disease that has significant effect on potato production, storage, and processing. …”

Image_1_Comparison of the extracellular vesicle proteome between glaucoma and non-glaucoma trabecular meshwork cells.tif by Fiona S. McDonnell (17106334)

“…Introduction<p>Extracellular matrix (ECM) materials accumulate in the trabecular meshwork (TM) tissue of patients with glaucoma, which is associated with a decrease in aqueous humor outflow and therefore an increase in intraocular pressure. …”

Relationship between overrepresentation in Ago2 IP and changes in mRNA levels due to miR-1 and miR-124. by David G. Hendrickson (257868)

“…Red lines correspond to mRNAs that were Ago2 IP targets but did not decrease significantly at the mRNA level; nevertheless, 20 of 22 mRNAs in this group are downregulated (log₂ change<0) at the mRNA level (P<10⁻⁵, one-way binomial test). …”

Data_Sheet_2_Genome-Wide Profiling of DNA Methylome and Transcriptome Reveals Epigenetic Regulation of Potato Response to DON Stress.xlsx by Yan Shi (166398)

“…However, potato production is affected by numerous biotic and abiotic stresses, among which Fusarium dry rot is a disease that has significant effect on potato production, storage, and processing. …”

<i>Fusobacterium nucleatum</i>-Induced Impairment of Autophagic Flux Enhances the Expression of Proinflammatory Cytokines via ROS in Caco-2 Cells by Bin Tang (56654)

“…<i>nucleatum</i> was enhanced with either autophagy pharmacologic inhibitors (3-methyladenine, bafilomycin A1) or RNA interference in essential autophagy genes (ATG5 or ATG12) in Caco-2 cells. …”

Primer pairs for RT-qPCR. by Yoichi Kurokawa (22290520)

“…Conversely, exposure to endogenous prooxidants (dopamine and adrenaline), certain food-derived polyphenols (chrysin and 3-<i><i>O</i></i>-methylquercetin), or 1,2-naphthoquinone led to a significant decrease (<0.5-fold) in Rmst expression. …”

Inhibition of DNA Methylation Alters Chromatin Organization, Nuclear Positioning and Activity of 45S rDNA Loci in Cycling Cells of <i>Q. robur</i> by Vedrana Vičić Bočkor (610205)

“…After treatment of the root cells with the methylation inhibitor 5-aza-2′-deoxycytidine, we observed an increase in the total level of rRNA transcripts and a decrease in DNA methylation level at the NOR-2 locus. …”