HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching. by Michael Anthony Ruiz (726055)

“…However, transfection of SUZ12 siRNA significantly reduced endothelial branching compared to HG+control siRNA. [NG+control siRNA = 5mM D-glucose + 100nM control siRNA, HG+control siRNA = 25mM D-glucose + 100nM control siRNA, HG+EZH2 siRNA = 25mM D-glucose + 100nM EZH2 siRNA, HG+SUZ12 siRNA = 25mM + 100nM SUZ12 siRNA; identical letters represent groups that are not significantly different; p < 0.05; n = 6; data expressed as mean ± SEM, normalized to U6 or β-actin and expressed as a fold change of NG+control siRNA].…”

Gene Ontology analysis reveals biological programs that are decreased during vertebrate tissue regeneration. by Sarah E. Mercer (108441)

Antibody response elicited by SARS-CoV-2 vaccines. by Chris Davis (647632)

Heparin (GAG-hed) inhibits LCR activity of Human Papillomavirus type 18 by decreasing AP1 binding-5 by Rita Villanueva (65963)

“…Nuclear extracts obtained from HeLa cells were exposed to GAG-hed at indicated concentrations for 10 min before labelled probe addition (Panels B and D). On panel A and C, complex specificity is denoted by competition assays with a 100 fold excess of indicated oligonucleotide competitor. …”

Relative expression (fold-change) of immune genes in mitogen-stimulated splenic lymphocytes. by Chaiwat Monmai (6377270)

WT1 siRNA decreases proliferation, pAKT, and Bcl2 expression. by Ayana E. Morales (17756335)

“…</b> RT-qPCR of WT1, p<0.05(*), vFLIP(ns), LANA, p<0.0001(****), K8.1, p<0.0001(****), and BCL2 p<0.05(*) in the setting of WT1 knockdown in ISLK BAC-16 with WT1 siRNA in comparison to a control siRNA using two-sided, unpaired student’s t-tests. …”

Identification of mutations that impair global folding. by Radhika Gopal (4692103)

“…Only one mutation T329A (red dot) resulted in markedly decreased V5 expression. …”

MeV induced <i>APOBEC3A</i> upregulation. by Pierre Khalfi (7868252)

Subjects:

Variants enriched in an <i>Ae</i>. <i>aegypti</i> cell line <i>(</i>Aag2) have increased fitness in Aag2 cells but decreased fitness in a human cell line (MRC-5). by Chelsea Cereghino (15188341)

TEM4 depletion decreases TEM4 mRNA and protein levels but no effect on spindle staining by the TEM4 antibody. by Diogjena Katerina Prifti (12988141)

Experimental Setup. by Mengnan Wu (769253)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”

Fold change of TIL subsets in paired TNBCs (N = 12 pts including 10 prim-met, and 2 met-met specimens) using log2 ratio of metastatic versus primary TNBC (n = 10, ●) or second recu... by Ting-Fang He (5210948)

Apoptosis inhibitor prevented the decrease of IIL ESP-induced TJs expression and alleviated barrier disruption of Caco-2 monolayer. by Qi Qi Lu (17721401)

Subjects:

Coupled negative feedback decreases the overall LG. by Rong Gao (476219)

DGAT-1 Inhibitor A922500 decreases the pro-inflammatory profile and cell death induced by SARS-CoV-2 infection and reduces the viral load in human monocyte. by Suelen Silva Gomes Dias (9928813)

Delayed boosting with ALVAC-HIV/AIDSVAX B/E or AIDSVAX B/E increases V1V2-specific IgG concentration and breadth. by LaTonya D. Williams (3140490)

<i>dnak14</i> mutant harbors a transposon insertion in the <i>dnaK</i> coding region and specifies a truncated DnaK protein. by Carissa Chan (18310140)

Ubiquitin ligases of the rat pineal gland whose expression is decreased at least 2-fold at night in the Hartley dataset. by Jerry Vriend (3756514)