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HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity
Published 2019Subjects: -
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<i>Dmxl2</i> knockdown in INS-1E cells decreases glucose-induced insulin release.
Published 2014“…In the presence of various concentrations of glucose (5 and 20 mM), <i>Dmxl2</i>-siRNA–transfected cells displayed only a small increase in insulin release, at a glucose concentration of 20 mM only, whereas a 2- to 3-fold increase was observed with NT siRNA-transfected cells. …”
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Data_Sheet_1_A Tool for Computation of Changes in Na+, K+, Cl− Channels and Transporters Due to Apoptosis by Data on Cell Ion and Water Content Alteration.ZIP
Published 2019“…New experimental data for staurosporine-induced apoptosis of human lymphoma cells U937 have been obtained: the time course of changes in cellular K<sup>+</sup>, Na<sup>+</sup>, Cl<sup>−</sup>, and water content, as well as Rb<sup>+</sup> fluxes as a marker of the Na/K pump activity. Using a newly developed computational tool, we found that alteration of ion and water balance was associated with a 55% decrease in the Na<sup>+</sup>/K<sup>+</sup>-ATPase rate coefficient over a 4-h period, with a time-dependent increase in potassium channel permeability, and a decrease in sodium channel permeability. …”
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5-FU induces a decrease in the total cell number in cultures of smooth muscle cells.
Published 2013“…We found an initial reduction of 20% at 0.01 mM up to a reduction of 70% in 10 mM of 5-FU. …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”
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Presentation_1_Eosinophils Decrease Pulmonary Metastatic Mammary Tumor Growth.pptx
Published 2022“…We found that IL5Tg mice exhibit reduced pulmonary metastatic colonization and decreased metastatic tumor burden compared to wild-type (WT) mice or eosinophil-deficient mice. …”