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20101
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20102
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20103
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20104
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20105
Missense Mutations in LRP5 Associated with High Bone Mass Protect the Mouse Skeleton from Disuse- and Ovariectomy-Induced Osteopenia - Fig 5
Published 2015“…<p>(A) The ratio of uterus wet weight to total body weight was decreased in the mice that underwent ovariectomy surgery (Ov) compared to sham-operated (Sh) littermates, among all genotypes. …”
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20106
Mean threshold current levels needed to evoke forelimb movements on stimulation of the right cerebral motor cortex.
Published 2014“…After TBI, the contralateral movement threshold (for left normal forelimb) was unchanged, whereas the ipsilateral movement threshold was decreased significantly at 5 weeks postinjury compared to sham (<i>p</i><0.05). tPA treatment further reduced the threshold current needed for ipsilateral forelimb movement compared to the saline controls (<i>p</i><0.05). …”
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20107
Experimental design and model validation.
Published 2023“…<p>(A) Diagram of overall study design. Wild-type (WT) and APPswe/PS1dE9 (AD) mice were bred to carry p38α exon 1 flanked by loxP sites and a tamoxifen-inducible Cre recombinase gene under control of a <i>Cx3Cr1</i> promoter. …”
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20108
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20109
RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis <i>In Vivo</i>
Published 2015“…Importantly, human monocyte-derived DCs treated with a chemical inhibitor for KDM5B resulted in increased innate cytokine levels as well as elicited decreased Th2 cytokines when co-cultured with RSV reactivated CD4<sup>+</sup> T cells. …”
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20110
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20111
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20112
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20113
Microarray and K-means cluster analyses of genes regulated by TRH and by thyroid hormone in TRH-deficient pituitary.
Published 2013“…B) In addition to the TSHβ genes, cluster 5 contained the Egr-1, NR4A1, Glt2, and Tmsb10 genes. …”
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20114
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20115
Evaluation of 309 molecules as inducers of CYP3A4, CYP2B6, CYP1A2, OATP1B1, OCT1, MDR1, MRP2, MRP3 and BCRP in cryopreserved human hepatocytes in sandwich culture
Published 2015“…MRP2 was induced by 27 compounds followed by MDR1 (16) > BCRP (9) > OCT1 (8) > OATP1B1 (5) > MRP3 (2).</p><p>3. CYP3A4 appeared to be down-regulated (≥2-fold decrease in mRNA expression) by 53 compounds, 10 for CYP2B6, 6 for OCT1, 4 for BCRP, 2 for CYP1A2 and OATP1B1 and 1 for MDR1 and MRP2.…”
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20116
Pathways Common to <i>HD</i> CAG and 3-NP Reveal Decreased Carbohydrate and Lipid Metabolism, with <i>HD</i> CAG-Specific Pathways Reminiscent of huntingtin Normal Function
Published 2007“…<div><p>(A) Venn diagrams summarize the results of GO analysis (biological process), showing the numbers of significantly altered (Increase, Decrease) <i>HD</i> CAG-specific, 3-NP-specific and shared GO terms, with the major categories of pathways listed below.…”
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20117
Piwi dissociates from mitotic nuage at the central spindle in a <i>klp10A</i>-dependent manner.
Published 2020“…Open arrowheads (D) point to a Piwi-positive nuage particle, sliding along and later releasing the MT bundle, without decreasing GFP-Piwi signal. …”
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20118
Compromised Purkinje cell dendritic arborization, reduction in glutamatergic synapses and ultrastructural alterations in the cerebellar cortex of <i>atc/atc</i> mice.
Published 2017“…<b>(G)</b> Immunostaining of sagittal cerebellar sections from 4 week-old mice reveals a significant decrease in the expression of vGlut1 both in PC-parallel fiber synapses in the ML as well as in granule cell-mossy fiber synapses in the IGL of the cerebellar cortex of <i>atc/atc</i> mice. …”
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20119
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20120