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19701
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19702
<em>Saccharomyces boulardii</em> Improves Intestinal Epithelial Cell Restitution by Inhibiting αvβ5 Integrin Activation State
Published 2012“…Indeed, by using cell adhesion assays, we showed that <em>Sb</em> supernatant contains heat sensitive molecule(s), with a molecular weight higher than 9 kDa, which decreased αvβ5 integrin-mediated adhesion to vitronectin by competing with the integrin. …”
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19703
All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex
Published 2024“…Our results reveal significant variations in the behavior of the immune complex structure across five different membrane compositions, which include POPC, POPA, DPPC, and DLPC phospholipids, and a mixed POPC/cholesterol system. …”
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19704
Table_1_Development of multiplex real-time PCR for simultaneous detection of SARS-CoV-2, CCoV, and FIPV.pdf
Published 2024“…</p>Methods and results<p>In this study, we developed a novel multiplex TaqMan-probe-based real-time PCR assay for the simultaneous detection and differentiation of SARS-CoV-2, CCoV, and FIPV. …”
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19705
TRPM7 regulates intracellular Ca<sup>2+</sup> and Mg<sup>2+</sup> concentration of cortical astrocytes.
Published 2015“…However, knockdown of TRPM7 in mouse cortical astrocytes significantly decreases intracellular Mg<sup>2+</sup> by 43.5% ± 9.8% (*, <i>p</i> < 0.05, n = 4). …”
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19706
Data Sheet 5_Regulatory mechanism of ABCB1 transcriptional repression by HDAC5 in rat hepatocytes under hypoxic environment.zip
Published 2025“…In the BRL hypoxia model, ABCB1 and SP1 expression decreased while HDAC5 expression increased. After SAHA treatment, ABCB1 and SP1 expression were upregulated while HDAC5 was downregulated. …”
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19707
Silencing TRPM7 in Mouse Cortical Astrocytes Impairs Cell Proliferation and Migration via ERK and JNK Signaling Pathways
Published 2015“…Knocking down TRPM7 with specific siRNA impairs the proliferation and migration of astrocytes by 40.2% ± 3.9% and 40.1% ± 11.5%, respectively. Consistently, inhibition of TRPM7 with 2-aminoethoxydiphenyl borate (2-APB) also decreases astrocyte proliferation and migration by 46.1% ± 2.5% and 64.2% ± 2.4%. …”
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19708
Structural mapping of collective dynamics profiles for the CDK5-p25, CDK6/V-cyclin and CDK9-cyclin T complexes.
Published 2017“…<p>Structural mapping of the GNM-based collective dynamics profiles driven by the slowest three modes is shown for the CDK5-p25 complex (pdb id 3O0G) (A), CDK6-Vcyclin complex (pdb id 2EUF) (B) and CDK9-cyclin T complex (pdb id 4EC8) (C). …”
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19709
Performance of the model with the inhibitory V0<sub>D</sub> pathways removed.
Published 2015“…Decreasing <i>α</i> causes two bifurcations: (i) transition from symmetric alternations of flexor activity, i.e. with a phase difference of Δ<i>φ</i> = 0.5, to alternations with a phase difference of Δ<i>φ</i> ≠0.5 at X<sub>7</sub> and then (ii) from alternation to synchronization of flexor activity at X<sub>6</sub>. …”
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19710
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19711
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19712
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19713
Inactivation of Topo IV leads to a specific inability to replicate the terminus region of the chromosome.
Published 2025“…<p>Replication profiles of growing wild-type, <i><i>gyrB</i></i><sup>ts</sup>, and <i><i>parE</i></i><sup>ts</sup> cells are plotted at 0, 1.5, and 3 hrs after temperature shift from 30°C to 43°C. …”
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19714
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19715
Table 5_Therapeutic potential of five frequently prescribed herbs in obesity-associated Hashimoto’s thyroiditis: insights from efferocytosis regulation.xlsx
Published 2025“…Moreover, TCM offers significant benefits in regulating lipid metabolism and decreasing systemic inflammation.</p>Methods<p>Targets of five high-frequency herbs (Hedysarum multijugum Maxim, Radix Bupleuri, Prunella vulgaris, Fritillaria thunbergii Bulbus, and Angelicae sinensis Radix) were obtained from the TCMSP and Swiss Target Prediction databases. …”
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19716
Inhibition of Neuroblastoma Tumor Growth by Ketogenic Diet and/or Calorie Restriction in a CD1-Nu Mouse Model
Published 2015“…Neuroblastoma growth reduction correlated with decreased blood glucose concentrations and was characterized by a significant decrease in Ki-67 and phospho-histone H3 levels in the diet groups with low tumor growth. …”
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19717
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19718
Changes after 45 minutes in the proportion of LTP, LTD or no plasticity responses observed in L5PyNs population induced by the HFS protocol in the presence of D1R agonist or antago...
Published 2015“…<p>(A and D) Percentages of L5PyNs displaying LTP, LTD or no plasticity in 129/Sv mice and 5-HT<sub>1A</sub>R-KO mice in control conditions. …”
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19719
Table_5_Integrative Analysis of LGR5/6 Gene Variants, Gut Microbiota Composition and Osteoporosis Risk in Elderly Population.DOCX
Published 2021“…The rs10920362 CT/TT genotype associated with a decreased relative abundance of Actinobacteria (β = −1.32, P < 0.001), Bifidobacteriaceae (β = −1.70, P < 0.001), and Bifidobacterium (β = −1.70, P < 0.001) compared to the CC genotype.…”
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19720
BrdU assay in control siRNA (blue bars) and in PAX6 knockdown (red bars) limbal epithelial cells (LECs) without and after 1µM or 5µM RA incubation for 48 hours.
Published 2025“…Significant p values (<0.05) are highlighted. BrdU assay shows a significantly lower proliferation rate in the PAX6 siRNA knockdown group than in control siRNA group (p < 0.001). 5µM RA treatment significantly decreased proliferation rate in controls (p = 0.025). …”