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Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters.
Published 2022“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”
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PLD2 and mTORC2 are required to convert increases in membrane tension to decreases in actin network assembly.
Published 2016“…Boxes in all box plots (B) extend from the 25th to 75th percentiles, with a line at the median. Whiskers extend to ×1.5 IQR (interquartile range) or the max/min data points if they fall within ×1.5 IQR.…”
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Inhibition of IL-17A at tumor sites decreases the intratumoral microvessel density.
Published 2013“…<p>(A) The endothelial maker CD31-stained sections of tumor tissue are shown in Ad-SNC and Ad-si-IL-17 treatment models, Ad-si-IL-17 treatment decreased the intratumoral microvessel density compared with Ad-SNC. …”
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The <i>P[syt<sup>P-L</sup>]</i> mutation decreases the Ca<sup>2+</sup> affinity of release and vesicular release probability, but the readily releasable pool is unchanged.
Published 2017“…<p>(A) Mean EJP amplitudes from <i>+/-;P[syt<sup>WT</sup>]/+</i> (filled black circles) and <i>+/-;P[syt<sup>P-L</sup>]/+</i> (filled red circles) larvae at Ca<sup>2+</sup> levels ranging from 0.05 mM—5.0 mM. …”
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499
Activin A decreases MPTP and LPS-induced inflammation.
Published 2017“…<p>Stereological quantification of the left SNpc demonstrated activin A significantly decreased the number of GFAP-immunoreactive cells (A) and Iba1-immunoreactive cells (B) in the SNpc following MPTP. …”
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