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nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
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HRMECs treated with SUZ12 siRNA demonstrate increased miR-200b expression, decreased VEGF expression and decreased endothelial branching.
Published 2015“…<b>E,F:</b> Tube formation assay to measure endothelial branching. …”
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1528
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1529
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1530
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1531
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1532
A Dietary Supplement Containing Cinnamon, Chromium and Carnosine Decreases Fasting Plasma Glucose and Increases Lean Mass in Overweight or Obese Pre-Diabetic Subjects: A Randomized...
Published 2015“…</p><p>Results</p><p>Four-month treatment with the dietary supplement decreased FPG compared to placebo (-0.24±0.50 <i>vs</i> +0.12±0.59 mmol/L, respectively, p = 0.02), without detectable significant changes in HbA1c. …”
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1533
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1539
Identification, Synthesis, and Biological Evaluations of Potent Inhibitors Targeting Type I Protein Arginine Methyltransferases
Published 2022“…In this study, we first identified several hit compounds against CARM1 by structure-based virtual screening (IC<sub>50</sub> = 35.51 ± 6.68 to 68.70 ± 8.12 μM) and then carried out chemical structural optimizations, leading to six compounds with significantly improved activities targeting CARM1 (IC<sub>50</sub> = 18 ± 2 to 107 ± 6 nM). …”
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1540
IDD388 Polyhalogenated Derivatives as Probes for an Improved Structure-Based Selectivity of AKR1B10 Inhibitors
Published 2016“…Next, by means of IC<sub>50</sub> measurements, X-ray crystallography, WaterMap analysis, and advanced binding free energy calculations with a quantum-mechanical (QM) approach, we have studied their structure–activity relationship (SAR) against both enzymes. …”